Dr. Soo Chan Lee's lab at Texas Tech University Health Sciences Center focuses on understanding the mechanisms behind fungal infections, particularly mucormycosis caused by Mucorales fungi. The lab investigates how certain proteins, including calcineurin and protein kinase A, contribute to the virulence of these fungi and explores new strategies for antifungal drug development. By identifying specific genetic links and pathways in these organisms, the lab aims to provide insights that could lead to more effective treatments for life-threatening fungal infections in immunocompromised patients.

Dr. Sharilyn Almodovar's lab investigates how the HIV virus affects the lungs and heart, particularly focusing on a condition known as Pulmonary Hypertension that can occur in people living with HIV. By studying how specific HIV proteins and genetic differences influence lung blood vessel function, the lab aims to uncover mechanisms of disease and potential new treatments. Their research combines cutting-edge techniques with both human cells and animal models to better understand the impact of HIV on lung health.