Eric C Martens · Microbiology & Immunology
Dr. Eric C. Martens' lab at the University of Michigan focuses on how dietary factors, particularly fiber and soy protein, influence gut health and the prevention of inflammatory bowel disease (IBD). They utilize mouse models to investigate the interactions between the gut microbiome and the mucus barrier, aiming to uncover mechanisms that could mitigate the risk of IBD. Their research could ultimately lead to better dietary recommendations and treatments for gut-related diseases.
Bethany B. Moore · Microbiology & Immunology
Bethany B. Moore's lab at the University of Michigan focuses on understanding how the immune system interacts with lung cells during injury and fibrosis. They study the role of specific immune and structural cells in managing lung health, especially how these interactions can influence infections and fibrosis. The lab aims to develop targeted therapies for lung diseases that arise from chronic inflammation and to improve the immune responses in fibrotic lungs.
Akira Ono · Microbiology & Immunology
Dr. Akira Ono's lab at the University of Michigan studies the HIV virus and how it infects host cells, particularly CD4+ T cells. They investigate the mechanisms of HIV assembly and entry into these immune cells, focusing on the roles of specific proteins and cellular processes that contribute to the infection cycle. Their research aims to identify new antiviral strategies to combat HIV by interfering with how the virus assembles and spreads within the body.
Philip D King · Microbiology & Immunology
Dr. Philip D. King's lab at the University of Michigan focuses on understanding how a specific protein, RASA1, regulates blood vessel development. They study how mutations in this protein can lead to serious vascular malformations in the brain, especially in children. By exploring the molecular mechanisms behind these conditions, the lab aims to find ways to prevent and treat such disorders.
Mark T. Anderson · Microbiology & Immunology
Dr. Mark T. Anderson's lab at the University of Michigan focuses on understanding how a specific type of bacteria, known as uropathogenic E. coli, causes urinary tract infections (UTIs), particularly in women of different ages. The lab studies the behavior of these bacteria from the initial colonization in the urinary tract to the development of acute infections. By comparing gene expression in young and postmenopausal women, the team aims to uncover how these infections occur and identify potential target for new treatments and prevention strategies.