Yao-Ying Ma · Pharmacology
Dr. Yao-Ying Ma's lab at Indiana University Indianapolis focuses on understanding how certain brain cells contribute to cocaine addiction and relapse. By studying the excitability of specific neurons in the motor cortex, the lab aims to uncover mechanisms behind drug-seeking behavior, especially after withdrawal. The ultimate goal is to identify new targets for preventing relapse in individuals dealing with substance use disorders.
Adrian Lynn Oblak · Biomedical Engineering · Pharmacology
Dr. Adrian Lynn Oblak's research lab focuses on understanding how environmental factors, particularly air pollution and certain fungi, influence the development and progression of Alzheimer's disease (AD). The lab investigates the role of peripheral immune cells, which are crucial in responding to pollutants, in exacerbating AD neuropathology. Through their studies, they aim to identify potential biological mechanisms that connect lung health and brain function, with the goal of finding ways to mitigate the impacts of these exposures on Alzheimer's disease.
William J Sullivan · Pharmacology
Dr. William J. Sullivan's lab focuses on understanding how the Toxoplasma gondii parasite persists in the brain as a latent form, which can reactivate in immunocompromised individuals. The lab is investigating the role of translation initiation factors in the formation of these latent cysts, aiming to discover new therapeutic targets that could help prevent serious infections caused by this parasite. By using innovative cell models and advanced techniques, the lab seeks to uncover the complex mechanisms involved in protein synthesis during the cyst formation process.