Dr. Yunmeng Liu's lab is focused on understanding how diabetes and hypertension are connected through the immune system, particularly looking at T cells. The research aims to uncover the mechanisms behind T cell activation and its impact on these diseases using mouse models. By exploring how certain signaling pathways involving ATP and insulin contribute to this connection, the lab hopes to identify new therapeutic targets to help reduce the risks associated with metabolic syndrome.

Dr. John D Imig's lab studies how certain molecules in the body, called epoxyeicosatrienoic acids (EETs), can help regulate blood flow and kidney function. They focus on how kidney damage, caused by things like lack of blood flow or blockages, can lead to long-term health issues like high blood pressure and chronic kidney disease. The lab uses techniques in genetics and pharmacology to explore how increasing levels of EETs can potentially prevent or restore kidney function and protect against high blood pressure.

Dr. Shengyu Mu's lab studies how immune cells, particularly T cells, contribute to high blood pressure, or hypertension. They focus on understanding the mechanisms of T cell activation in the kidneys and how these cells become long-lasting memory cells that can affect salt retention and blood pressure regulation. The goal of the research is to uncover new strategies for treating hypertension by targeting specific immune processes that contribute to the disease.

Dr. Rupak Pathak's lab focuses on understanding how platelets interact with the immune system, especially after exposure to harmful radiation. This research is vital for developing new therapies to protect individuals from immune disorders caused by nuclear events. The lab aims to find ways to improve immune response and protect against organ damage by examining platelet behaviors and their interactions with immune cells.