Peter L Jones · Pharmacology
Dr. Peter L. Jones leads a research lab at the University of Nevada Reno focused on developing innovative therapies for Facioscapulohumeral muscular dystrophy (FSHD) using CRISPR technology. Their work aims to repress the harmful gene DUX4 in muscle cells to alleviate symptoms of this genetic disorder. The lab's efforts include the design of advanced delivery systems for CRISPR components in muscle tissue and testing these in mouse models to establish effective treatment strategies.
Lai Wen · Pharmacology
Dr. Lai Wen's lab focuses on understanding how certain proteins regulate the adhesion of immune cells, specifically neutrophils, to blood vessel walls during inflammation. This research is crucial for tackling cardiovascular diseases, as inflammation plays a major role in heart-related issues. By exploring the interactions between proteins like kindlin-3 and talin-1, the lab aims to uncover new mechanisms that could lead to innovative therapies to reduce tissue damage during inflammatory responses.