Dr. Benedek Erdos's lab at the University of Vermont focuses on understanding how stress affects blood pressure and heart health. The research investigates a specific signaling pathway in the brain that can lead to heightened sensitivity to stress, which contributes to the development of hypertension. By studying this mechanism, the lab aims to find new ways to treat high blood pressure that is aggravated by psychological stressors.

Dr. Osama F Harraz's lab at the University of Vermont focuses on understanding how blood flow to the brain is regulated and how that process is affected in conditions like hypertension. They study a protein called Piezo1, which acts as a sensor in blood vessel cells, enabling them to respond to changes in blood flow. By examining how this protein functions in different scenarios, the lab aims to identify new strategies for treating cardiovascular diseases that impact brain health.

Dr. Masayo Koide's lab studies how high levels of the hormone aldosterone can negatively affect small blood vessels in the brain, potentially leading to cognitive issues or dementia. The research focuses on understanding the mechanisms by which this hormone impacts blood flow in very small brain vessels and aims to identify new ways to protect brain health. This work is important for developing strategies to mitigate cognitive decline associated with small vessel diseases.