Dr. Baljit Khakh's lab at UCLA focuses on the role of astrocytes, a type of brain cell, in understanding brain functions and diseases, particularly Alzheimer's disease. The lab investigates how astrocytes interact with neurons and other brain cells within neural circuits to maintain brain health and how these processes can become dysfunctional in conditions like aging and Alzheimer’s. By examining protein changes in these cells, the lab aims to develop new diagnostic and therapeutic approaches for neurological diseases.

Professor Stephen C. Cannon's research lab at UCLA focuses on understanding a rare condition called hypokalemic periodic paralysis (HypoPP), which leads to sudden muscle weakness. The lab investigates how specific genetic mutations affect muscle function and explores new treatment options, including pharmacological interventions and gene editing techniques. Their work aims to improve the quality of life for individuals affected by this condition and to find more effective ways to manage and potentially prevent muscle weakness associated with it.

Dr. Stephanie Correa's lab at UCLA focuses on how brain circuits influence eating behaviors, especially regarding sex differences. Her research investigates how specific neurons in the hypothalamus interact with hormones like estradiol to regulate appetite. By studying these neural pathways, the lab aims to unravel the complex mechanisms linking hormonal regulation and feeding, which is crucial for addressing issues like obesity and eating disorders, particularly in women.

Dr. Elaine Hsiao's lab at UCLA focuses on understanding how the gut microbiome affects the responses to antidepressant treatments, particularly during pregnancy. By studying the interactions between the gut microbiome and selective serotonin reuptake inhibitors (SSRIs), the lab aims to improve treatments for antenatal depression and reduce potential risks to both mothers and their babies. The research could lead to safer and more effective strategies for managing depression during pregnancy.

Dr. Yousang Gwack's lab at UCLA explores how genetic factors influence the immune system, particularly focusing on T cells and their response to autoimmune diseases. By examining mitochondrial function and integrity, the lab seeks to uncover the mechanisms that make some T cells more prone to attacking the body, which can lead to diseases such as arthritis and diabetes. Their work combines advanced genetic screening in mice with sophisticated imaging techniques to better understand these processes and push towards new treatments.

Dr. David W. Walker's lab at UCLA focuses on understanding how changes in mitochondria contribute to the aging process and Alzheimer's disease. By studying how mitochondrial DNA is released into cells and triggers inflammation, the lab aims to uncover potential therapeutic strategies to combat age-related diseases. Utilizing Drosophila models, the research explores the links between mitochondrial function, immune responses, and longevity.

Dr. Xinshu Grace Xiao's lab at UCLA focuses on understanding the genetic factors related to Alzheimer's Disease (AD). The lab investigates how certain genetic variants affect post-transcriptional regulation of mRNA, particularly through the analysis of 3' untranslated regions (UTRs) and the role of RNA derived from retrotransposable elements. Their research aims to uncover new insights into the mechanisms that contribute to AD, potentially leading to innovative therapeutic strategies.