Dr. Dmitri N Ivanov's research focuses on understanding how a protein called SAMHD1 helps the body's immune system fight against HIV-1, the virus that causes AIDS. This protein regulates the levels of deoxynucleotides, which are vital for various cellular functions including DNA repair. His lab studies the biochemical properties and regulatory mechanisms of SAMHD1 to explore how it can enhance antiviral defense in non-dividing immune cells.

Dr. Jean X Jiang's lab focuses on developing innovative treatments for triple-negative breast cancer (TNBC), an especially aggressive form of breast cancer that disproportionately affects younger patients and women of color. The lab is working on creating novel drugs that target adenosine receptors to inhibit tumor growth and enhance anti-tumor immunity. By employing advanced technologies in drug design and testing in animal models, the aim is to generate effective therapies that improve the survival of patients with this challenging disease.

Dr. Thomas G. Boyer's lab focuses on understanding uterine fibroids, which are non-cancerous tumors affecting women's health. The research investigates how specific molecular changes, particularly in RNA modifications, contribute to the formation and progression of these tumors. By studying these mechanisms, the lab aims to develop new therapeutic approaches to treat uterine fibroids more effectively.