Dr. Matthew W. Mosconi's lab focuses on understanding Fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disorder that affects motor skills, particularly in older adults. The lab strives to identify biomarkers and mechanisms that characterize disease progression in FXTAS, studying both genetic factors and brain changes over time. By comparing individuals with FXTAS to those without the syndrome, the research aims to provide insights that could lead to better tracking of the disease and potential treatments.

Dr. Jomella Thompson's lab at the University of Kansas focuses on understanding and preventing youth violence, particularly among racial and ethnic minorities. The lab evaluates community-based strategies like the ThrYve (Together Helping Reduce Youth Violence) model and the REVIVE hospital violence prevention program. By studying the impact of these initiatives, the lab aims to improve public health outcomes and develop effective prevention practices in high-violence neighborhoods.

Dr. Irina Tikhanovich's lab focuses on understanding the mechanisms behind alcohol-associated liver disease (ALD). The research aims to investigate how certain liver cells signal to aid in the resolution of fibrosis after alcohol withdrawal. By studying the role of the Acute Phase Response, the lab hopes to develop new therapeutic strategies to improve liver recovery among patients with ALD.

Dr. Michael J. Soares' lab focuses on understanding how certain cells in a developing embryo interact with the mother's uterus to support a successful pregnancy. The lab studies specialized cells called trophoblasts, which are vital for implantation and placental development. By exploring the processes that regulate these cells, the lab aims to uncover the causes of pregnancy complications and identify potential new ways to help manage these issues.

Dr. Hubert M. Tse's lab focuses on improving islet transplantation for type 1 diabetes treatment by exploring innovative encapsulation methods. They aim to create a protective environment for pancreatic cells to prevent immune rejection, using a special coating that modulates immune responses. This research could lead to better outcomes for patients receiving islet transplants.

Dr. Eric Dennis Vidoni's lab at the University of Kansas Medical Center focuses on understanding how different types of exercise impact brain health and cognition in older adults. Their research investigates the effects of aerobic and resistance training on cognitive performance, brain structure, and overall physical function. By leveraging community-based exercise programs, they aim to develop strategies that promote successful aging and help prevent diseases like Alzheimer's.

Dr. Ning Wang's lab at the University of Kansas Medical Center studies how changes in mitochondria can affect brain functions related to Alzheimer's disease. They are particularly interested in how an increase in lactate production can modify proteins in ways that may harm brain cells and contribute to the disease. By understanding these processes, the lab aims to identify new ways to diagnose and treat Alzheimer’s disease.

Dr. Heather M. Wilkins leads a research lab at the University of Kansas Medical Center focusing on the role of amyloid precursor protein (APP) in mitochondrial function and mitophagy, particularly in the context of Alzheimer’s disease. The lab investigates how APP interacts with mitochondrial components to influence energy production and cellular health. This work has important implications for understanding Alzheimer’s disease and developing potential therapeutic strategies.

Dr. Michael S. Wolfe's lab at the University of Kansas focuses on understanding the mechanisms of Alzheimer's disease, particularly how a key enzyme called gamma-secretase processes amyloid precursor proteins. The lab investigates both genetic mutations that lead to familial Alzheimer's disease and broader factors that influence neuron degeneration. By exploring these processes, the team aims to discover new treatment strategies that might benefit individuals suffering from Alzheimer's, especially those with the late-onset form of the disease.