Loading university
Douglas R Seals — Dr. Douglas R. Seals' lab focuses on understanding how lifestyle interventions, like heat therapy and inspiratory muscle strength training, can improve cardiovascular health, particularly in mid-life and older adults. They investigate how these methods can lower high blood pressure and enhance blood vessel function, helping to mitigate risks for heart disease and other age-related issues. The research aims to explore both the effectiveness of these interventions and the underlying biological mechanisms involved.
Leslie Anne Leinwand — Dr. Leslie Anne Leinwand's lab focuses on understanding how muscle cells adapt and change in response to various stimuli such as exercise and genetic mutations. They study myosin, a key protein in muscle function, to explore how it is replaced and repaired over time, particularly in relation to heart and skeletal muscles. The lab uses advanced imaging techniques to measure protein turnover and investigate how these processes are influenced by factors like biological sex and disease-causing mutations.
Karolin Luger — Dr. Karolin Luger's research focuses on understanding how the protein PARP1 interacts with DNA and chromatin in cells, especially in the context of cancer treatment. By studying PARP1's structure and function, her lab aims to develop more effective drugs that can enhance cancer therapy, particularly for tumors with DNA repair deficiencies. Their work could lead to innovations in how these drugs are applied and how they work at the molecular level.
Marie T Banich — Dr. Marie T. Banich's lab focuses on understanding how emotional thoughts can be removed from working memory and how various factors influence this process. They conduct research using brain imaging and machine learning techniques to explore the neural mechanisms involved in thought suppression, particularly in the context of psychiatric disorders. The lab also studies the effects of adolescent substance use and environmental factors on brain development and mental health outcomes.
Natalie G. Ahn — Dr. Natalie G. Ahn's lab at the University of Colorado studies how proteins regulate cellular responses, especially focusing on the MAP kinase ERK2 involved in signaling pathways. By understanding the dynamics of enzyme activation and the effects of varying strengths of signaling, her research aims to uncover mechanisms that can lead to new cancer treatments. Students in this lab will gain hands-on experience in biochemistry and cell biology, contributing to important discoveries in molecular biology.
Amy E Palmer — Dr. Amy E Palmer's lab studies the role of zinc in cell biology and its impact on human health. The research focuses on how zinc dynamics influence cellular processes like gene expression and cell cycle, aiming to develop advanced tools for tracking RNA in live cells. This work seeks to improve our understanding of zinc as a signaling molecule and its connection to diseases.
Kenneth P Wright — Dr. Kenneth P. Wright's lab at the University of Colorado focuses on understanding circadian rhythms, particularly how disruptions can lead to sleep disorders like Delayed Sleep-Wake Phase Disorder (DSWPD). The research aims to identify biomarkers for circadian rhythms in peripheral tissues and develop new treatment strategies to improve health and daily functioning for affected individuals.
David L Bentley — Dr. David L. Bentley's lab at the University of Colorado Denver focuses on understanding how genes get turned into messenger RNA (mRNA), the vital molecules that carry genetic information. They study the processes involved in mRNA production, including how the mRNA is created and then modified before it functions in the body. By examining these critical steps, the lab aims to find out what goes wrong in diseases like cancer when these processes are disrupted.
Dylan J Taatjes — Dr. Dylan Taatjes' lab at the University of Colorado focuses on understanding how RNA polymerase II, an essential enzyme that helps transcribe DNA into RNA, is regulated during the process of gene expression. The lab combines biochemical experiments and advanced cellular assays to investigate the mechanisms that control RNA polymerase II activity, which is critical for normal cell function and can lead to diseases like cancer and neurological disorders when disrupted.