Dr. Jeff Kuret's lab at Ohio State University focuses on understanding tau aggregates, which play a crucial role in Alzheimer's disease and related conditions. The research explores how tau proteins misfold and form unique structures that contribute to neurodegeneration. By studying these aggregates, the lab aims to develop better diagnostic tools and therapies for tauopathies by clarifying the molecular mechanisms involved in tau aggregation and how they can be targeted by small molecules.

Dr. Maria M. Mihaylova's research lab at Ohio State University focuses on understanding how aging affects cancer metabolism. Her team studies the metabolic changes in tumors and their surrounding environments as people age, with the goal of discovering new insights into cancer initiation and progression. By using advanced techniques to analyze single cells, they aim to uncover how diets and microbiome metabolites influence these processes, potentially transforming how we treat cancers in older individuals.