A. Joshua Wand · Biochemistry
Professor A. Joshua Wand's lab at Texas A&M Agrilife Research focuses on understanding how proteins work and how their structures affect their functions in health and diseases. The lab studies the impact of entropy, a measure of disorder, on the stability and function of proteins, particularly in the context of diseases like Parkinson's. By exploring these relationships, the lab aims to uncover new pathways for disease intervention and develop strategies to address various health issues related to protein dysfunction.
James C Sacchettini · Biochemistry
Dr. James C. Sacchettini's lab focuses on improving tuberculosis treatment by exploring the mycobacterial cell wall, which is crucial for the bacteria's survival. The team investigates how to make existing antibiotics more effective by understanding and exploiting synergies between different drugs. Their ultimate goal is to develop new combination therapies that can overcome drug resistance and accelerate TB treatment.