Dr. Ronen Sumagin's lab at Northwestern University studies ulcerative colitis, a chronic inflammatory bowel disease affecting many people. The lab focuses on understanding why certain biologic therapies, which are often expensive, work poorly for many patients. They investigate the role of specific types of immune cells called neutrophils in the gut and how these cells might be keeping treatment from being effective, aiming to find new ways to help patients respond better to their therapies.

Dr. M. Luisa Iruela-Arispe's lab at Northwestern University focuses on understanding how genetic mutations and cellular mechanisms contribute to vascular abnormalities and cancer-related complications. The lab investigates specific genetic mutations that create fragile blood vessels responsible for serious conditions like arteriovenous malformations. Additionally, they study the impact of cancer on the body's vascular system, particularly how it can lead to weight loss and cachexia, to identify potential therapeutic interventions.