Dr. Cheryl A. London's lab at Tufts University focuses on improving cancer therapies through innovative research involving dogs. The lab works on enhancing the immune response in canine osteosarcoma by activating dendritic cells and also investigates clonal hematopoiesis in dogs to understand its implications for cancer treatment. Through clinical trials and the study of immune responses, the research aims to translate findings from canine models to improve human cancer therapies.

Dr. Sergei Mirkin's lab at Tufts University investigates how certain DNA structures, specifically repeating sequences, can lead to genetic disorders and cancers. His research focuses on understanding the mechanisms behind repeat expansions that cause over fifty hereditary diseases, including various neurodegenerative disorders. By uncovering these mechanisms, the lab aims to contribute valuable insights into both basic biology and potential medical treatments.

Dr. Megan Kiely Mueller's lab at Tufts University focuses on understanding how relationships between adolescents and their pet dogs can help young people cope with social anxiety. By exploring the specific dynamics of these relationships, the lab aims to develop effective strategies to support teenagers struggling with mental health issues. The research includes extensive observation and analysis of both behavioral and physiological responses in youth as they interact with their dogs.

Cammie Lesser's lab at Tufts University focuses on understanding how the bacterium Shigella survives and replicates inside human intestinal cells. By studying how Shigella manipulates the immune system, particularly through inflammatory cell death processes, the lab aims to uncover new strategies for preventing and treating severe infections caused by this pathogen. This research is vital, especially in light of rising antibiotic resistance.

Dr. Sam R Telford's lab focuses on enhancing biosafety and biocontainment in research related to infectious diseases. The team trains staff in advanced technical skills required for working with dangerous pathogens and develops resources to enable rapid responses to emerging health threats, such as pandemics. By fostering collaboration with academic and industry partners, the lab aims to improve regional preparedness in managing public health challenges.

Dr. Harry P. Selker leads the Tufts Clinical and Translational Science Institute, which focuses on enhancing clinical research and improving public health through innovative team science. The lab works with various partners to train new researchers, develop groundbreaking methods, and foster collaboration throughout the research continuum. Their ultimate goal is to bridge the gap between scientific research and practical health solutions.

Dr. Yi-Pin Lin's lab focuses on understanding how wild birds help maintain Lyme disease bacteria, which is a significant health concern in the U.S. The research aims to uncover the immune responses of birds that allow these bacteria to persist without causing the birds harm. By studying this interaction, the lab hopes to inform public health strategies to reduce the risk of Lyme disease in humans.