Dr. J. Mark Cline's lab focuses on investigating the long-term effects of radiation exposure using a unique cohort of nonhuman primates. They explore how radiation affects health over time, looking at diseases like diabetes and heart conditions that develop after exposure. The lab collaborates with other researchers to share findings and improve our understanding of radiation injury, which is crucial for developing better emergency responses and treatments.

Dr. Katherine Loree Cook's lab at Wake Forest University Health Sciences focuses on understanding how diet and the gut microbiome interact to influence breast cancer risk, particularly in obese individuals. The lab investigates how metabolites produced by gut bacteria, such as hippurate, can signal through specific receptors to reduce tumor growth and improve treatment responses. Through preclinical models and clinical studies, the research aims to uncover novel strategies to link diet, microbiome health, and cancer prevention.

Dr. Waldemar Debinski's lab focuses on innovative treatments for glioblastoma (GBM), a highly aggressive brain cancer. They are pioneering the use of drug conjugates that target specific receptors over-expressed in GBM cells, aiming to improve patient outcomes by combining direct tumor killing with immune system activation. The lab's research involves testing these therapies in preclinical models, which may pave the way for new clinical treatments.

Dr. Gagan Deep's lab focuses on understanding Alzheimer's disease and related dementias through innovative methods like 'liquid biopsies'. They investigate how a special diet known as the Modified Mediterranean-Ketogenic Diet impacts brain function and biomarkers in individuals with mild cognitive impairment. Their research also looks at how different types of brain cells communicate and contribute to the progression of dementia, especially considering diverse populations.

Dr. William H. Gmeiner's lab focuses on developing innovative nanotechnology solutions to enhance cancer treatment, specifically for metastatic colorectal cancer (mCRC). Their research is particularly centered on a specialized polymer designed to improve drug delivery and effectiveness while reducing toxicity. By utilizing advanced formulations, such as lipid nanoparticles, they aim to directly target tumors and improve the outcomes of chemotherapy.

Dr. Wei Zhang's lab at Wake Forest University focuses on addressing health disparities in lung cancer treatment, particularly between Black and White patients. The lab investigates how differences in tumor biology and metabolism affect treatment responses, aiming to develop novel therapeutic strategies that enhance immune responses in cancer. Their work combines cutting-edge genomic technologies and preclinical models to discover new ways to improve outcomes for underserved populations.