Dr. Timothee Lionnet's research lab at NYU focuses on understanding the molecular mechanisms of aging and transcription regulation. The lab uses synthetic biology and advanced imaging techniques to explore how specific proteins are involved in the aging process and how they regulate gene expression. By manipulating these proteins, the lab aims to develop innovative strategies to combat aging-related diseases and improve gene regulation technologies.

Dr. Laura Beth Johnson Mcintire's lab focuses on understanding how lipid metabolism changes in the brain due to Alzheimer's disease. They aim to create a detailed atlas of lipid distribution in the brain to help identify key changes that could lead to new biomarkers or therapeutic targets for Alzheimer's. By studying both human brains and mouse models, the lab seeks to connect findings in lipid dysregulation to cognitive decline and disease progression in Alzheimer's disease.

Dr. Peiying Liu's lab focuses on improving our understanding and diagnosis of cognitive impairment related to small vessel disease in the brain, which affects many elderly patients, including those with Alzheimer's Disease. They are developing a new MRI technique called normalized cerebrovascular reactivity (nCVR) that measures how well blood vessels in the brain respond to changes in gas levels, which could help identify vascular issues that contribute to cognitive decline. This work is important for creating better diagnostic tools for dementia and cognitive health in older adults.

Dr. Changchun Liu's research lab focuses on developing innovative methods for HIV viral load testing using CRISPR technology. The lab aims to create a rapid and cost-effective diagnostic tool that can be used in resource-limited settings, addressing the urgent need for accessible HIV testing. This work combines advanced biomedical engineering techniques with molecular biology to improve public health outcomes related to HIV/AIDS.

Dr. Terence Gade's lab at the University of Pennsylvania focuses on improving diagnosis and treatment of liver cancer, particularly hepatocellular carcinoma (HCC). They work on developing advanced imaging techniques and patient-derived models to better understand tumor behavior and predict treatment responses. This research aims to enhance patient outcomes by creating more effective therapies based on personalized data from these models.

Dr. Kejia Cai's lab at the University of Illinois at Chicago focuses on improving the diagnosis and treatment of liver cancer, specifically hepatocellular carcinoma (HCC). By using a novel pig model that imitates human cancer characteristics, the lab explores advanced imaging techniques that can help determine tumor aggressiveness and guide better patient care. Their work has the potential to refine how we diagnose and manage liver cancer through noninvasive methods.

Dr. Emilie Roncali's lab at UC Davis focuses on improving cancer treatment, particularly for liver cancer, using innovative computational tools. They aim to develop personalized medical strategies through a 'digital twin' of the liver, which helps optimize treatment planning. The lab also works on advancing nuclear imaging technology, leveraging artificial intelligence to enhance the speed and accuracy of imaging systems used in cancer diagnostics.

Dr. Dong-Hyun Kim's lab focuses on developing innovative treatments for liver cancer using a combination of immunotherapy and radioembolization techniques. The lab is dedicated to enhancing the effectiveness of immune checkpoint blockades by targeting them specifically to tumor sites, potentially improving patient outcomes. Their research aims to make therapies safer and more effective, with the ultimate goal of treating patients who would otherwise have limited options.

Dr. Ali Pirasteh's lab focuses on improving the diagnosis and treatment of chronic liver diseases, which affect a large portion of the global population. The primary research involves developing a new non-invasive imaging technique using positron emission tomography (PET) to detect liver fibrogenesis, the process that leads to liver scarring and various complications including liver failure. By targeting activated liver cells, this method aims to provide critical information about liver health and treatment efficacy over traditional biopsy methods, enhancing care for millions who suffer from chronic liver conditions.

Dr. James H. Holmes' lab focuses on improving liver cancer treatment using a combination of advanced imaging techniques. They are developing a system that integrates ultrasound and MRI for real-time guidance during liver tumor ablation procedures. This innovative approach aims to enhance the accuracy and effectiveness of these treatments, ultimately improving patient outcomes.

Dr. Li Feng's lab focuses on developing advanced MRI techniques to improve the diagnosis and management of chronic liver diseases, particularly metabolic-associated steatotic liver disease (MASLD). They are pioneering a new method that provides non-invasive imaging biomarkers to assess liver inflammation and fibrosis. This research aims to offer alternative solutions to invasive procedures like liver biopsies.

The lab led by Dr. Jonathan F. Lovell focuses on innovative approaches to tackle some of the most challenging health issues, such as tuberculosis and pancreatic cancer. Through the development of advanced vaccine technologies and light-activated drug delivery systems, the lab aims to improve treatment efficacy significantly and contribute to better patient outcomes. Students involved in this lab will gain hands-on experience with cutting-edge biomedical engineering techniques and contribute to groundbreaking research in vaccine development and cancer therapies.

Dr. Matthew Tirrell's lab at the University of Chicago focuses on using targeted nanomedicine to address serious lung diseases like acute respiratory distress syndrome (ARDS) and pulmonary fibrosis. Their innovative approach seeks to modify specific cell types during different phases of lung disease, particularly in response to viral infections such as COVID-19. The lab aims to develop new therapies that can effectively reduce lung injury and fibrosis, offering hope for improved treatment options in the future.

Dr. Jaime Mata's lab at the University of Virginia focuses on improving the diagnosis and management of acute cellular rejection in lung transplantation using innovative Hyperpolarized Gas MRI technology. This research aims to enhance the early detection of rejection, allowing for timely interventions and better outcomes for lung transplant patients. The lab integrates advanced imaging techniques with genomic profiling to create a comprehensive understanding of the immune responses involved in lung allograft health.

Dr. Craig H. Meyer's lab at the University of Virginia focuses on developing innovative magnetic resonance imaging (MRI) techniques for assessing lung health. By utilizing a novel 0.55 Tesla MRI scanner, the lab aims to create more effective imaging methods that can visualize both lung structure and function concurrently, which is particularly important for diagnosing chronic lung diseases without exposing patients to harmful radiation. Their work not only seeks to enhance MRI technology but also strives to make advanced lung imaging more accessible, especially for vulnerable populations like children and pregnant women.

Dr. Louise Henderson's lab focuses on improving the health and monitoring of lung cancer survivors through innovative imaging techniques and data analysis. The research aims to reduce the risks of cancer recurrence and identify better strategies for lung cancer screening, especially for diverse populations. Using advanced deep learning methods and analysis of routine chest CT scans, the lab develops personalized surveillance strategies that tailor follow-up care to individual patient risks.

Dr. Jonathan Mamou's lab focuses on improving the detection and evaluation of lymph nodes, particularly in determining whether they harbor metastatic cancer. By leveraging advanced quantitative ultrasound techniques, his research aims to create better diagnostic tools that can differentiate between cancerous and benign conditions in lymph nodes during routine medical procedures. This work not only seeks to enhance cancer staging but also to facilitate more appropriate treatment strategies for patients.

Dr. Jaewon Yang's lab focuses on enhancing imaging techniques for lymphedema, a condition where fluid accumulates due to lymphatic system failure. His team is working on developing new tools to improve lymphoscintigraphy, a standard imaging method used for diagnosing lymphedema. By utilizing advanced techniques like deep learning, they aim to provide clearer images and better analysis to help improve patient care for those affected by this condition.

Dr. Chao Ma's lab focuses on enhancing the treatment of gliomas, a common type of malignant brain tumor, through advanced imaging techniques. They are developing a novel imaging technology that combines Magnetic Resonance Spectroscopic Imaging (MRSI) with machine learning to achieve high-resolution metabolic images of tumors. This research aims to improve the accuracy of radiation therapy planning by precisely mapping tumor boundaries, which is crucial for better patient outcomes in glioma treatment.

Dr. Robert H. Mach's lab at the University of Pennsylvania focuses on advancing our understanding of neurodegenerative diseases by developing advanced imaging techniques. In particular, the lab is working on creating new Positron Emission Tomography (PET) ligands that help visualize protein clumps associated with conditions like Parkinson's disease and frontotemporal dementia. Through collaborations with top universities, the lab aims to improve diagnostic methods and therapeutics for these critical neurological disorders.