Dr. Andrew J Saykin's research lab focuses on understanding Alzheimer's disease and related dementias through a comprehensive study of brain aging. The lab collaborates on a large-scale project that collects and analyzes longitudinal clinical, genetic, and neuroimaging data from diverse populations, particularly a Korean cohort. The goal is to identify early biomarkers and improve diagnostic and therapeutic strategies for Alzheimer's disease.

Dr. Rohan Dharmakumar's lab is focused on improving treatment strategies for patients recovering from heart attacks. The team studies how blood flow restoration after a heart attack can sometimes cause additional damage, particularly through a condition called intramyocardial hemorrhage. By using advanced cardiac imaging techniques, they are working to develop new therapies that could reduce heart failure risk and improve recovery outcomes for affected patients.

Dr. Kara E. Garcia's lab focuses on understanding the mechanics of brain development, particularly how brain folds form in infants. They investigate the factors that influence brain structure, especially during the crucial stages of growth in the womb and shortly after birth. By using advanced MRI techniques and computational modeling, they aim to link these developmental processes to various neurological and psychiatric disorders.

Dr. Adrian Lynn Oblak's research lab focuses on understanding how environmental factors, particularly air pollution and certain fungi, influence the development and progression of Alzheimer's disease (AD). The lab investigates the role of peripheral immune cells, which are crucial in responding to pollutants, in exacerbating AD neuropathology. Through their studies, they aim to identify potential biological mechanisms that connect lung health and brain function, with the goal of finding ways to mitigate the impacts of these exposures on Alzheimer's disease.

Dr. Paul Territo's research lab at Indiana University focuses on understanding neuroinflammation in Alzheimer's disease and related dementias. The lab studies P2X7 receptors, which play a significant role in communication between brain cells and are involved in the inflammatory processes that lead to neurodegeneration. By investigating these mechanisms using advanced mouse models, the lab aims to develop potential treatments to prevent cognitive decline associated with these diseases.

Dr. Yu-Chien Wu's lab at Indiana University Indianapolis focuses on understanding neurodegenerative diseases like Alzheimer's by using advanced MRI techniques. The lab explores how these imaging methods can detect changes in brain synapses associated with memory decline. By studying animal models and applying findings to human health, they aim to improve early diagnosis and treatment options for Alzheimer's disease.