Linda C Hsieh-Wilson · Chemistry
Dr. Linda C Hsieh-Wilson's lab at Caltech is investigating the roles of chondroitin sulfate glycosaminoglycans (CS GAGs) in the brain, focusing on their structure, functions, and effects on neuroplasticity and inflammation. The research aims to understand how specific chemical modifications of CS GAGs influence processes that are crucial for memory, healing, and neurodegenerative diseases like Alzheimer's and multiple sclerosis. Students in the lab will engage in both chemistry and neurobiology techniques to explore these important interactions.
Shu-Ou Shan · Chemistry
Dr. Shu-Ou Shan's lab at Caltech focuses on understanding how proteins are made and folded correctly inside cells, which is essential for maintaining a healthy balance of proteins in our bodies. The research investigates specific processes like how proteins get chemical modifications while being formed and how helper proteins exist to guide these processes. By studying these intricate mechanisms, the lab aims to uncover why certain diseases occur when protein production goes wrong.
Scott Kevin Cushing · Chemistry
The Cushing lab at Caltech focuses on advancing methods in time-resolved fluorescence, which is essential for measuring biological signals with high precision. They are developing miniaturized devices that utilize entangled photon sources integrated with photonics technology, making portable medical diagnostics more accessible. Their work aims to improve health equity by allowing broader applications of these advanced measurement techniques in various biological and medical fields.