The lab of Dr. Raymond E. Moellering at the University of Chicago focuses on developing innovative strategies to combat triple-negative breast cancer (TNBC) by targeting specific transcription factors that drive tumor growth. Using engineered synthetic transcriptional repressors (STRs), the lab aims to inhibit the activity of key proteins that enable cancer cells to survive in stressful environments. This research not only seeks to advance our understanding of cancer biology but also to create novel therapeutic options that could improve patient outcomes.

Dr. Gregory A. Voth's lab focuses on using advanced computer simulations to better understand complex biological processes, specifically related to HIV-1 and cellular mechanics. By modeling how proteins interact with cell membranes and each other, the lab aims to uncover vital steps in the life cycle of the HIV virus and the mechanisms that allow cells to move and interact. This research has implications for developing new treatments for diseases related to HIV and cellular dysfunction.