Satoshi Namekawa · Microbiology & Immunology
Dr. Satoshi Namekawa's research focuses on understanding how epigenetic mechanisms control the development of sperm and eggs, which are crucial for reproduction. The lab investigates complex processes like spermatogenesis and oogenesis to uncover how these processes ensure the continuity of life from one generation to the next. Their findings hope to enhance our knowledge of germline biology and contribute to advancements in reproductive health.
Scott C Dawson · Microbiology & Immunology
Scott C. Dawson's lab at UC Davis studies the mechanisms of how the Giardia lamblia parasite attaches to the intestines. They are particularly focused on a unique organelle called the ventral disc, which allows Giardia to adhere to the intestinal wall, causing diseases like diarrhea. By using advanced imaging and genetic tools, the lab aims to uncover how this attachment occurs and to find potential treatments against Giardia infections.
Andreas J Baumler · Microbiology & Immunology
Dr. Andreas J. Baumler's lab focuses on understanding the complex interactions between gut microbiota, host health, and infectious diseases. Their research includes studying how probiotics like E. coli Nissle 1917 protect against infections from pathogens such as Salmonella, examining the impact of gut microbiota changes on chronic kidney disease, and probing the links between diet, gut bacteria, and inflammatory bowel disease. The lab employs a range of innovative techniques to uncover the mechanisms that maintain gut health and combat various diseases.
Dennis J. Hartigan-O'Connor · Microbiology & Immunology
Dr. Dennis J. Hartigan-O'Connor's lab at UC Davis focuses on understanding and improving treatments for HIV infection. The lab investigates how T-cell responses can be harnessed to develop effective vaccines that prevent and control HIV. By exploring the interactions between T-cells and antibodies, the lab aims to innovate new therapeutic approaches that could lead to lasting immune protection against HIV.
Janine M Lasalle · Microbiology & Immunology
Dr. Janine M Lasalle's lab at UC Davis focuses on understanding how environmental factors, particularly exposure to polychlorinated biphenyls (PCBs), affect brain development and behavior, especially in relation to autism spectrum disorders. The lab investigates the molecular mechanisms behind neurodevelopmental disorders, including the roles of specific genes and epigenetic changes, aiming to uncover why boys are more severely affected than girls. Through innovative use of human samples and mouse models, the research seeks to identify protective mechanisms in the brain that could lead to new therapies for autism.
Satya Dandekar · Microbiology & Immunology
Dr. Satya Dandekar’s research focuses on eliminating HIV using innovative strategies that involve mesenchymal stem cells (MSC) in a monkey model. The lab investigates how these stem cells can enhance the immune system's ability to target and eradicate the virus. This work is crucial for developing new treatments and vaccines against HIV and understanding severe immune responses.
Katherine S Ralston · Microbiology & Immunology
Dr. Katherine Ralston's lab at UC Davis focuses on understanding how the amoeba Entamoeba histolytica causes disease in humans by invading tissues and avoiding immune responses. They discovered a unique method by which this amoeba nibbles on human cells, allowing it to survive and cause harm. The lab uses various techniques to study this process, which has broader implications for understanding microbial behavior and immune evasion.
Stefan Rothenburg · Microbiology & Immunology
Dr. Stefan Rothenburg's lab focuses on developing innovative strategies to combat viruses that are transmitted by animals and insects. They are working on a project to create recombinant antiviral proteins (called REAVRs) that can sense and inhibit the replication of various viruses. By improving the immune response in mosquitoes, they aim to reduce the risk of zoonotic diseases affecting humans.