Dr. Sarah M. Doore's lab at the University of Florida focuses on understanding how bacteriophages, which are viruses that infect bacteria, interact with their hosts. The lab specifically studies a group of bacteriophages called Moogleviruses that target pathogenic bacteria responsible for diarrhea. By exploring the mechanisms of infection and replication of these viruses, the research aims to develop new strategies for phage therapy, particularly in combating antibiotic-resistant infections.

Dr. Liang Zhou's research lab focuses on understanding how specific immune cells in the gut, particularly RORgt+ lymphocytes, maintain tissue health and respond to infections. The lab investigates the roles of mitochondrial function and iron metabolism in the upkeep and activity of these immune cells, which could lead to new treatments for diseases like inflammatory bowel disease and infections. By exploring the intricate relationships between these cells and their environment, the research aims to uncover mechanisms that are crucial for gut health and immunity.

Dr. Clayton Mathews' lab focuses on understanding how autoimmune processes trigger Type 1 diabetes (T1D) by studying the pancreatic islet cells. They investigate specific proteins that may change in structure due to various chemical modifications, potentially serving as signals for the immune system to attack. By characterizing these changes in affected individuals, the lab aims to discover new biomarkers and insights that could help prevent T1D in at-risk people.

Dr. Cuong Q Nguyen's lab at the University of Florida focuses on understanding Sjogren's Disease, an autoimmune disorder affecting the salivary and lacrimal glands. The lab uses advanced proteomics to uncover unique proteins that could trigger this disease. By identifying these proteins and their interactions with immune cells, the lab aims to discover new therapies to prevent or treat Sjogren's Disease, especially in those who are genetically predisposed.