Adeen Flinker · Neuroscience
Dr. Adeen Flinker's research lab focuses on understanding how our brains process speech by analyzing the way sound is integrated over time in the auditory cortex. They use advanced techniques to study patients who have had neurosurgery, allowing them to capture detailed brain activity as individuals listen to speech. The goal is to uncover how we recognize words and sentences and to develop new treatments for speech disorders.
Xinyu Zhao · Neuroscience
Dr. Xinyu Zhao's lab at the University of Wisconsin-Madison focuses on understanding the role of a specific protein, FMRP, in brain development, particularly in primates and humans. This research is crucial for uncovering the mechanisms behind Fragile X Syndrome and other neurodevelopmental disorders like autism. By examining how FMRP influences neuronal maturation and energy metabolism, the lab aims to contribute to the development of better therapies for these conditions.
Howard S Fox · Neuroscience
Dr. Howard Fox's lab focuses on understanding how HIV and opioid use affect the brain on a cellular level. They use advanced techniques like single-cell RNA sequencing to examine how these factors interact and influence various brain cells. This research helps uncover important information about the neurological implications of HIV and drug abuse, with the potential to improve treatments and outcomes for affected individuals.
John J Foxe · Neuroscience
Dr. John J. Foxe's research lab at the University of Rochester focuses on understanding how the brain develops in children and adolescents. His team is part of the ABCD Study, the largest long-term investigation of brain health and development in the U.S., tracking over 11,000 children as they grow. The lab examines various factors, including mental health, substance use, and social experiences, to see how they influence brain development and cognitive abilities over time.
Anna Fracassi · Neuroscience
Dr. Anna Fracassi's lab at the University of Texas Medical Branch at Galveston focuses on understanding the complex relationship between microglia and tau proteins in Alzheimer's disease. They are particularly interested in how certain brain-derived tau oligomers can promote cognitive resilience in individuals who show signs of Alzheimer's pathology but remain cognitively intact. By investigating the unique characteristics of these oligomers and the role of microglia, they aim to uncover novel therapeutic targets to combat this devastating disease.
Kuan Hong Wang · Neuroscience
Dr. Kuan Hong Wang's lab at the University of Rochester focuses on understanding how aging and Alzheimer's disease affect a specific brain network called the frontal-insular network. They study the structural and functional changes in this network using advanced imaging techniques and mouse models. Their aim is to uncover the reasons behind cognitive decline in Alzheimer's and explore ways to improve cognitive function through targeted interventions.
David John Irwin · Neuroscience
Dr. David Irwin's research lab at the University of Pennsylvania focuses on understanding frontotemporal dementia (FTD), a serious condition that affects younger individuals and leads to significant changes in behavior, personality, and cognitive function. The lab investigates how glial cells and iron accumulation contribute to neurodegeneration in different types of FTD, particularly those influenced by tau or TDP-43 proteins. By analyzing human brain tissue and integrating advanced imaging techniques, the lab aims to uncover patterns that could lead to better diagnosis and treatment options for FTD.
Heather J Fullerton · Neuroscience
Dr. Heather J. Fullerton's lab focuses on understanding the disease process and treatment options for a condition called focal cerebral arteriopathy (FCA), which is a leading cause of strokes in children. The lab is conducting a clinical trial (FOCAS) to compare two treatment strategies using corticosteroids to see which one leads to better health outcomes for affected children. They aim to ensure that children receiving treatment have the best chance of recovery and improvement in their neurological health.
Stefano Fusi · Neuroscience
Dr. Stefano Fusi's lab at Columbia University focuses on understanding how the dentate gyrus, a part of the hippocampus, contributes to cognitive functions like memory and learning, especially in the context of aging and diseases like Alzheimer's. The lab studies adult hippocampal neurogenesis, the process of generating new neurons in the brain, which decreases with aging and is associated with cognitive decline. By exploring this process through genetic and pharmacological approaches, they aim to discover new methods to restore memory function in older individuals.
Vikram Gadagkar · Neuroscience
Dr. Vikram Gadagkar's lab focuses on understanding how the brain of female songbirds processes and evaluates male songs, which can reveal insights into social behaviors and interactions. By studying the neural circuits involved in mate choice, the lab aims to explore the underlying mechanisms of social evaluation, which are relevant to various human social disorders. The research combines approaches from neurobiology, ethology, and computational biology to establish the female songbird as a model for understanding these complex behaviors.
Fen-Biao Gao · Neuroscience
Dr. Fen-Biao Gao's lab focuses on understanding frontotemporal dementia (FTD), a serious condition that affects behavior and language primarily in younger individuals. They explore the disease using advanced models like fruit flies and neurons derived from stem cells to uncover the genetic and molecular basis of FTD. The ultimate goal is to identify new targets for therapy and to help in the search for effective treatments for this challenging neurodegenerative disorder.
Hannah Gardener · Neuroscience
Dr. Hannah Gardener's research lab focuses on understanding how exposure to certain harmful chemicals, known as PFAS, affects brain health, particularly in relation to cognitive decline and dementia. The lab is investigating how PFAS may influence lipid metabolism and vascular health, which are critical factors in the development of Alzheimer's disease. By studying diverse populations over long periods, the lab aims to shed light on the connections between these pollutants and neurodegenerative conditions, ultimately aiming to inform public health strategies.
Kamel Khalili · Neuroscience
Dr. Kamel Khalili's lab is focused on finding a cure for HIV using advanced gene editing technologies, specifically CRISPR. The lab aims to enhance the immune response and eliminate the HIV virus that remains hidden in the body despite treatment. Through innovative research and collaboration, they are developing targeted therapies that could lead to sustainable control or elimination of the virus.
Suzanne M Leal · Neuroscience
Dr. Suzanne M. Leal's research focuses on understanding the genetic factors behind age-related hearing loss (ARHL) and tinnitus, particularly in diverse populations. She is also investigating the genetic causes of intellectual disability (ID), aiming to identify specific genes involved across various ethnic groups. By leveraging advanced genetic analysis tools and extensive datasets, her lab seeks to improve diagnosis and treatment strategies for these conditions, ultimately aiming to address health disparities.
Yin Shen · Neuroscience
Dr. Yin Shen's lab at UCSF focuses on understanding the genetic factors that contribute to Alzheimer's disease, specifically how risk genes and their variants influence gene expression and related biological functions. The lab uses advanced techniques such as CRISPR and single-cell analysis to study the interactions between these genetic factors and the disease. By examining nerve cells and brain organoids, the lab aims to uncover new insights that could lead to better risk predictions and therapeutic targets for Alzheimer's disease.
Simona Ghetti · Neuroscience
Professor Simona Ghetti's lab focuses on understanding how toddlers learn and retain vocabulary, as well as the effects of type 1 diabetes on neurocognitive development in children. By studying the brain processes involved in word retention in young children and the cognitive challenges faced by children with diabetes, the lab aims to uncover important insights that can improve educational strategies and health interventions. This research is crucial for developing effective support for children with language development issues and those affected by chronic health conditions.
Joseph G Gleeson · Neuroscience
Dr. Joseph Gleeson's lab at the University of California, San Diego is focused on understanding the genetic and environmental factors contributing to Meningomyelocele, a common congenital condition known as Spina Bifida. The lab aims to explore how genetic mutations interact with folic acid exposure during pregnancy to influence the risk of this condition. By studying families affected by Spina Bifida, the lab seeks to identify genetic markers that could lead to better prevention and treatment strategies for this serious birth defect.
Jeremy N Rich · Neuroscience
Dr. Jeremy N. Rich's lab focuses on understanding and treating glioblastoma, a highly aggressive brain cancer. The lab investigates how the metabolism of tumor cells affects their growth and survival, exploring the role of dietary interventions and aging in tumor development. Researchers use cutting-edge techniques to analyze the unique cellular behaviors within glioblastoma and aim to develop novel therapeutic strategies based on their findings.
Michal Schnaider Beeri · Neuroscience
Dr. Michal Schnaider Beeri's lab at Rutgers focuses on understanding the complex roles of glycoproteins in Alzheimer's disease and related disorders. By studying the modifications on brain proteins, their work aims to identify new biomarkers and potential treatments that can help preserve cognitive and motor function in aging individuals. The lab utilizes advanced techniques and large datasets to explore how an active lifestyle may influence brain health through these glycoproteins.
Qiang Zhang · Neuroscience
Dr. Qiang Zhang's lab at the University of Iowa focuses on understanding Alzheimer’s disease, particularly how glucose metabolism impacts the progression of the disease. They use rodent models to investigate the role of glycolysis in neurodegeneration, with the goal of developing new treatments. The lab’s research may lead to innovative therapies that could change the way Alzheimer’s disease is managed.