Dr. Michael D. Greicius's lab at Stanford University focuses on Alzheimer's disease, particularly the genetic factors that influence risk for the disease. Using advanced techniques like long-read sequencing, the lab explores how variations in the APOE gene and other relevant genes affect Alzheimer's risk in individuals of different ancestries. The ultimate goal is to identify new therapeutic targets that may lead to better treatments for this devastating disease.

Dr. Katrin Andreasson's lab at Stanford University focuses on understanding the roles of immune cells in cognitive decline related to aging and Alzheimer's disease. The research explores how signaling pathways, particularly involving inflammatory signals like prostaglandin E2 (PGE2), affect the function of both peripheral myeloid cells and brain microglia. By investigating these mechanisms, the lab aims to identify potential therapies that could improve cognitive function and mitigate age-related decline.

Dr. Helen Bronte-Stewart's lab focuses on developing innovative therapies to address cognitive decline in Parkinson's disease, particularly before it progresses to dementia. The lab is investigating the use of deep brain stimulation targeting the Nucleus Basalis of Meynert, which is involved in cognitive and motor functions. By optimizing stimulation patterns and patient selection, the research aims to improve cognitive and cognitive-motor outcomes for individuals with Parkinson's disease.

Dr. Marion Buckwalter's lab focuses on understanding how blood-brain barrier dysfunction contributes to cognitive decline in patients who have experienced a stroke. They investigate the long-term effects of stroke on brain health, specifically how inflammation and vascular changes may lead to post-stroke dementia. The lab aims to develop biomarkers that help predict which stroke survivors are at risk for cognitive impairment, paving the way for better management and treatment strategies.

Dr. Maarten G Lansberg's lab at Stanford University focuses on improving prevention strategies for stroke recurrence. They are conducting the CLARITY trial, which aims to evaluate whether adding cilostazol to standard treatment can significantly lower the risk of further strokes and cardiovascular events in a diverse population. This research is vital as it seeks to address the underutilization of cilostazol in the United States, potentially benefiting millions of stroke survivors with a safe and affordable treatment option.

Dr. Elizabeth Mormino's lab at Stanford University investigates how memory decline occurs in aging and early Alzheimer's disease. They focus on understanding how changes in the brain's structure and function, specifically in the hippocampus, relate to memory loss. By using cutting-edge imaging techniques and biofluid analysis, her team aims to develop models that predict individual memory decline, helping to identify early pathways of Alzheimer's before major symptoms develop.

Dr. Michelle Monje-Deisseroth's lab at Stanford University focuses on understanding how neurons contribute to the growth and formation of low-grade gliomas, a common type of brain tumor, particularly in children with Neurofibromatosis type 1 (NF1). Their research aims to explore the interactions between nerve cells and tumor cells to enhance treatment options and reduce long-term side effects in young patients. The lab employs various techniques to study the biological mechanisms behind these tumors and how they can be targeted for better therapies.

Dr. Kathleen Lombard Poston's lab at Stanford University focuses on understanding the role of gut health in neurological disorders, particularly Lewy Body Diseases like Parkinson's Disease. The research aims to explore how changes in gut immune responses and microbiota may contribute to the progression of these diseases. By studying the gut-brain interaction through innovative techniques, the lab hopes to identify potential new strategies for prevention and treatment.

Dr. Jennifer L. Raymond's lab at Stanford University focuses on understanding how learning influences brain function, particularly in the context of sensory processing and motor control. The lab investigates how the brain's neural circuits adapt their signal processing capabilities through experience, aiming to understand fundamental processes like synaptic plasticity that can lead to improved recovery from neural disorders. By combining experimental techniques with computational models, the lab seeks to reveal insights that could innovate clinical strategies for balancing and eye movement disorders.