Dr. Yong Wan's research lab at Emory University focuses on understanding how certain proteins involved in breast cancer, specifically B7-H4 and CD73, can evade the immune system and resist treatment. By studying how these proteins are modified and regulated, the lab aims to uncover new strategies to improve treatment outcomes, especially in aggressive types of breast cancer like triple-negative breast cancer (TNBC). Their work could lead to the development of novel therapies that enhance the body's ability to fight cancer.

Dr. Lih-Shen Chin's lab at Emory University focuses on understanding Lewy body dementia (LBD), which includes conditions like Parkinson's disease dementia and dementia with Lewy bodies. The research aims to uncover the molecular mechanisms that contribute to LBD's development and how it differs from Alzheimer's disease. By analyzing proteins and sugars in the brain, the lab hopes to identify new diagnostic markers and treatments for this challenging form of dementia.

Dr. Ellen J. Hess's lab at Emory University studies dystonia, a condition that causes involuntary muscle contractions. Their research focuses on understanding why dystonia is more common in females and how hormonal differences might influence the disease. By using advanced mouse models, the lab aims to determine the genetic and physiological factors contributing to sex differences in dystonia, which could lead to better diagnoses and treatments in the future.

Dr. Stephen Traynelis's lab at Emory University focuses on understanding how glutamate receptors function in the brain and their role in neurological diseases. The team employs advanced techniques like electrophysiology and cryo-electron microscopy to explore how genetic variations in these receptors can affect synaptic function and contribute to disorders like Alzheimer's and Parkinson's disease. By developing new therapeutic compounds, they aim to improve treatments and identify precision medicine strategies for brain-related conditions.

Dr. Lian Li's lab at Emory University focuses on understanding Alzheimer's disease (AD) through groundbreaking research aimed at identifying new biomarkers and therapeutic targets. The lab investigates the role of glycosylation, particularly sialylation, in AD pathology by analyzing human brain specimens to uncover critical molecular changes. Their work aims to improve diagnosis and develop potential new interventions for this complex disease.

Dr. Dionna Whitney Williams leads a research lab focused on understanding how substance use, specifically cocaine and cannabis, affects pregnant women living with HIV and their placentas. The lab investigates the mechanisms by which these substances may disrupt antiretroviral treatment effectiveness and promote inflammation, which can lead to adverse outcomes for both mothers and their babies. The research aims to identify ways to improve health interventions and treatment for this vulnerable population.

Dr. Zixu Mao's lab at Emory University focuses on understanding the molecular mechanisms involved in Alzheimer’s and Parkinson’s diseases. The lab investigates how cellular processes, particularly involving exosomes and lysosomes, respond to stress and contribute to neurodegeneration. By studying these processes, the lab aims to uncover new therapeutic targets and improve our understanding of how these devastating diseases progress.

Dr. Thomas L. Kukar's lab at Emory University focuses on understanding the role of a protein called progranulin in neurodegenerative diseases like Alzheimer's and frontotemporal dementia. The lab studies how loss of this protein leads to problems in the lysosomes, which are cell structures responsible for breaking down waste, and how this dysfunction contributes to diseases. By exploring potential therapies using components of progranulin, the lab aims to develop treatments that could help those suffering from these conditions.

Dr. Todd E Golde's lab at Emory University studies Alzheimer's Disease (AD) to understand how amyloid proteins impact brain health and function. They investigate the interactions between amyloid and other proteins to figure out new ways to treat AD by potentially harnessing the immune system. The lab aims to discover optimal immune treatments that could benefit patients while minimizing harm, contributing valuable insights to our understanding of dementia and broader neurodegenerative diseases.

Dr. Thota Ganesh's lab at Emory University focuses on developing new treatments for Alzheimer's disease, particularly through targeting a specific receptor involved in brain inflammation. They are working on small-molecule drugs that can potentially slow down the progression of Alzheimer's by reducing neuroinflammation and improving cognitive function. The research aims to create effective therapies that offer hope to the millions affected by this debilitating condition.

Dr. Renee D Read's lab at Emory University is focused on finding new treatments for glioblastoma, which is a very aggressive brain cancer. The lab investigates how certain proteins, YAP and TAZ, contribute to the growth of these tumors and how they can be inhibited using an existing drug called verteporfin. By understanding these mechanisms, the team aims to improve treatment options for patients with glioblastoma and possibly other related cancers.