Dr. Kin Sing Stephen Lee's research lab focuses on developing new treatments for Alzheimer's disease, which is a growing concern as the population ages. The lab specifically aims to create inhibitors for an enzyme called soluble epoxide hydrolase (sEH), which may alleviate symptoms of the disease. Researchers will investigate how to improve the efficacy of these inhibitors to ensure they effectively reach the brain and work optimally.

Dr. Nathan Tykocki's lab focuses on understanding how our bladder feels full as it fills with urine. They study the mechanical properties of the bladder wall and how these properties influence our sensation of needing to void. By using advanced techniques from both engineering and physiology, the lab aims to uncover the connection between bladder mechanics and sensory nerve signaling, which could lead to better treatments for bladder dysfunction.

Dr. Howard C. Crawford's lab investigates how collagen proteins contribute to the progression of pancreatic cancer. By studying a specific receptor that interacts with collagen, the lab aims to uncover new insights into how these proteins influence cancer behavior and identify potential targets for treatment. The ultimate goal is to improve survival rates for patients suffering from pancreatic ductal adenocarcinoma.

Dr. Norbert Kaminski's lab studies how cannabis use impacts inflammation in people living with HIV, particularly focusing on the effects on brain health. The research addresses how monocytes, a type of immune cell, become activated and contribute to neuroinflammatory damage in HIV-infected individuals. By investigating the relationship between cannabis use and inflammation, this work aims to improve our understanding of HIV-associated neurocognitive disorders and explore potential therapeutic options.

Dr. Cheryl Rockwell's lab focuses on understanding how dietary additives, specifically tert-butylhydroquinone (tBHQ), affect the immune response to influenza. They aim to uncover the mechanisms behind how tBHQ impairs T cell function, which is crucial for fighting viral infections and achieving effective vaccinations. This research could lead to better predictions about how certain substances in our diets might influence our immunity to diseases.

Dr. Neera Tewari-Singh's lab focuses on understanding the harmful effects of certain chemical agents known as vesicants, like mustard gas and phosgene oxime, specifically how they damage the lungs after skin contact. The lab aims to uncover the role of mast cells in this process, which could lead to new treatment strategies for those affected by these toxic agents. Their research is important for developing therapies for acute and long-term lung injuries caused by chemical exposure.

Dr. Stephanie W Watts' lab at Michigan State University investigates the role of perivascular adipose tissue (PVAT) in maintaining vascular health. The lab aims to understand how PVAT interacts with blood vessels and influences blood pressure regulation, which is crucial for preventing cardiovascular diseases. The research employs a variety of animal models and innovative techniques to explore how physiological changes impact PVAT function and, ultimately, cardiovascular health.