Dr. Mark Gillespie's lab at the University of South Alabama focuses on understanding how lung cells respond to low oxygen levels and the role of mitochondrial DNA in lung inflammation. The research aims to uncover new mechanisms that regulate gene expression during hypoxia and explore how mitochondrial damage contributes to lung diseases. By studying these processes, the lab seeks to identify potential therapeutic targets for treating conditions like pulmonary hypertension and acute lung injury.

Dr. Thomas C. Rich's lab at the University of South Alabama focuses on understanding how cells communicate internally to regulate their functions. Specifically, the lab studies airway smooth muscle cells and how different receptors within these cells manage signals that are crucial for controlling muscle contraction and relaxation. This research is vital for developing new treatments for asthma, a common respiratory condition affecting many people.