David Hoadley Ellison · Physiology
The lab led by David Hoadley Ellison focuses on understanding the diverse cell types in the kidney, specifically in regions crucial for solute retention. By employing advanced techniques to analyze these cells in health and stress conditions, the research aims to unravel mechanisms that may lead to kidney dysfunction and related diseases. Students in this lab will learn about the unique roles of different kidney cell types and how they respond to dietary changes and drug treatments.
Bonnie J. Nagel · Mathematics & Statistics · Physiology
Dr. Bonnie J. Nagel's lab focuses on understanding how children's cognitive and emotional development is affected by various factors, including mental health issues and environmental influences. The lab uses advanced mathematical and computational approaches to refine diagnostic tools that help clinicians identify and predict child psychopathology. By analyzing large datasets, including electronic medical records and brain imaging data, the lab aims to improve the diagnosis and treatment of mental health conditions in children.
Sue A Aicher · Physiology
Dr. Sue A Aicher's lab focuses on understanding the mechanisms behind ocular pain and light sensitivity, especially in conditions like migraine and dry eye disease. The research involves studying how pain and light sensing in the eye are connected and how immune responses may influence these phenomena. By examining these interactions in rodent models, the lab aims to uncover potential new treatments for these common and distressing conditions.
Xiangshu Xiao · Physiology
Dr. Xiangshu Xiao's lab at Oregon Health & Science University focuses on developing new drugs for triple negative breast cancer (TNBC), which is a particularly aggressive subtype of breast cancer. The lab is working on small molecules that can inhibit the RuvBL1/L2 complex, which is important for repairing DNA damage in cancer cells. This research aims to create therapies that selectively target cancer cells without harming healthy cells, improving treatment options for patients with this challenging disease.