Dr. Stella M Papa's lab at Emory University focuses on understanding and treating Parkinson's disease (PD), a progressive neurological disorder characterized by the loss of dopamine-producing cells. The lab studies the changes in dopamine signaling and striatal neuron function that occur in PD, with the goal of developing new therapeutic strategies. They utilize advanced animal models and gene therapy techniques to target specific aspects of the disease, hoping to enhance treatment outcomes and improve patients' quality of life.

Dr. Ellen J. Hess's lab at Emory University studies dystonia, a condition that causes involuntary muscle contractions. Their research focuses on understanding why dystonia is more common in females and how hormonal differences might influence the disease. By using advanced mouse models, the lab aims to determine the genetic and physiological factors contributing to sex differences in dystonia, which could lead to better diagnoses and treatments in the future.

Dr. Howard H. Chang's lab focuses on developing innovative statistical methods to analyze the health effects of environmental exposures. The research aims to improve our understanding of how various environmental factors influence health outcomes, especially in vulnerable populations. Their work involves using advanced statistical techniques, including Bayesian analysis and machine learning, to address complex epidemiological questions.

Dr. Gari David Clifford's lab focuses on utilizing advanced digital technologies and artificial intelligence to improve healthcare outcomes. They are developing tools to enhance the detection of Alzheimer's disease through eye-tracking to evaluate memory, and creating low-cost ultrasound technology to monitor maternal and fetal health in underserved communities. These innovative approaches aim to make critical health assessments more accessible and equitable across diverse populations.

Dr. Farzad Fereidouni's lab focuses on developing a new microscopy technique to improve the evaluation of kidney fibrosis, a condition that affects many patients with chronic kidney disease. The lab aims to create a rapid and accurate tool for detecting fibrosis directly from commonly used tissue slides, ultimately enhancing patient diagnosis and treatment outcomes. This research blends advanced imaging technology with practical applications in renal pathology.

Dr. Candace C. Fleischer's lab at Emory University focuses on measuring and understanding brain temperature, particularly after injuries such as strokes. The research aims to develop new, non-invasive techniques using magnetic resonance imaging to monitor brain temperature, which is crucial for patient recovery. By combining these techniques with advanced simulations, the lab seeks to improve treatment and prognostic evaluations for patients with cerebrovascular diseases.

Christina Gavegnano's lab at Emory University researches how to reduce HIV infection specifically within the central nervous system (CNS), which is a major barrier to curing the virus. By studying the drug baricitinib, the lab aims to see if it can effectively decrease HIV levels in the brain and improve the health of individuals living with HIV. The lab combines clinical studies with animal models to explore innovative treatments that might one day lead to a cure for HIV, improving the lives of those affected by the virus.

Dr. Stephen Traynelis's lab at Emory University focuses on understanding how glutamate receptors function in the brain and their role in neurological diseases. The team employs advanced techniques like electrophysiology and cryo-electron microscopy to explore how genetic variations in these receptors can affect synaptic function and contribute to disorders like Alzheimer's and Parkinson's disease. By developing new therapeutic compounds, they aim to improve treatments and identify precision medicine strategies for brain-related conditions.

Dr. Kyle Biegasiewicz's research lab focuses on developing innovative enzymes that can improve chemical reactions important for drug manufacturing. By studying haloperoxidase enzymes, the lab aims to create more environmentally friendly and selective methods for introducing halogens into organic compounds. This research could lead to better pharmaceuticals with enhanced therapeutic properties.

Dr. Khalid S. Salaita's lab at Emory University focuses on understanding and innovating diagnostic techniques related to blood coagulation and platelet activity. The research aims to develop new technologies to detect heparin-induced thrombocytopenia (HIT) more quickly and accurately, while also exploring the role of mechanical forces in cellular processes. The lab works at the intersection of chemistry and biology to create tools that can revolutionize how we diagnose and manage various blood-related medical conditions.

Dr. Mirko Paiardini's lab focuses on understanding how the body's immune system, particularly natural killer (NK) cells, can be optimized to fight HIV infections. The research aims to identify new treatments that enhance NK cell activity and the effectiveness of broadly neutralizing antibodies to control HIV without the need for continuous antiretroviral therapy. By studying viral control mechanisms in animal models, the lab seeks to develop innovative strategies that could lead to the eradication of HIV in humans.

Dr. Una T. O'Doherty's lab at Emory University focuses on understanding HIV, particularly why HIV reservoirs behave differently in various patients. The lab studies the role of different types of T cells, especially naive CD4+ T cells, which were previously thought to be less significant in HIV persistence. The team uses advanced techniques like machine learning and sequencing to reveal insights that could lead to new ways of reducing the size of the HIV reservoir and improving treatment strategies.

Dr. Rafick Pierre Sekaly's lab focuses on understanding and overcoming HIV infection. They study the immune system's role in maintaining the virus and explore therapeutic strategies, such as the use of IL-10 inhibitors, to restore immune function aiming for an HIV cure. By combining advanced techniques from different research fields, the lab aims to identify mechanisms that contribute to the HIV reservoir and develop innovative interventions for lasting solutions.

Dr. Eric Hunter's lab focuses on understanding the immune system's response to HIV infections, particularly how these responses differ between men and women. They seek to uncover mechanisms that could lead to better vaccines and treatments. The lab conducts research involving both human cohorts and nonhuman primate models to explore effective responses to HIV and factors that affect viral loads and immune activation.

Hyunsuk Shim's lab at Emory University focuses on improving imaging techniques for better radiation therapy planning in brain cancer patients. By utilizing spectroscopic MRI, the lab aims to enhance tumor detection and guide more effective treatment strategies, potentially leading to longer survival rates for patients with aggressive brain tumors. The research is centered on developing advanced imaging methods and software tools to better identify infiltrative tumor margins that are often missed by conventional MRI.

Dr. Anice C. Lowen's lab at Emory University studies how influenza A viruses spread among humans and other animals. They use advanced techniques to understand the biology of the virus, how it interacts with different hosts, and the factors that influence transmission. Their work aims to improve public health strategies for controlling influenza outbreaks and pandemics.

Dr. Erik C.B. Johnson's research lab at Emory University focuses on understanding Alzheimer's disease, particularly the less commonly studied early-onset cases that affect individuals under 65. By comparing the biological changes in early-onset Alzheimer's with later-onset and genetically inherited forms of the disease, the lab aims to uncover specific protein alterations that characterize these conditions. The ultimate goal is to improve diagnostic tools and treatment strategies for all forms of Alzheimer's disease, tailoring them for younger patients.

Dr. Lian Li's lab at Emory University focuses on understanding Alzheimer's disease (AD) through groundbreaking research aimed at identifying new biomarkers and therapeutic targets. The lab investigates the role of glycosylation, particularly sialylation, in AD pathology by analyzing human brain specimens to uncover critical molecular changes. Their work aims to improve diagnosis and develop potential new interventions for this complex disease.

Dr. Steven H. Liang's lab at Emory University focuses on developing advanced imaging techniques to better understand and treat Alzheimer's disease and related neuropsychiatric disorders. The research primarily involves creating novel PET ligands that can visualize specific receptors and enzymes in the brain to improve diagnosis and treatment options. The lab combines innovative chemistry with cutting-edge imaging technology to explore critical biological processes underlying these conditions.

The research lab led by Dr. Anant Madabhushi at Emory University focuses on using advanced imaging and computational techniques to improve cancer treatment outcomes. The lab's projects aim to develop innovative tools that predict patient responses to immunotherapy, identify risks associated with prostate cancer, and assess treatment needs for oral cavity cancers. By analyzing tissue images and using machine learning, they strive to enhance precision medicine in oncology.