Dr. Thomas M. Wisniewski's lab at NYU studies the cognitive impacts of COVID-19 on older adults, especially those who may develop Alzheimer's disease or related dementias. They focus on identifying biomarkers in the blood that could predict cognitive decline following COVID-19 infection. By examining patients over time, the lab aims to understand how COVID-19 affects brain health and what factors contribute to cognitive impairment in this population.

Dr. Teresa Davoli's lab focuses on understanding how DNA mutations occur in human cells and their role in diseases like cancer. The lab develops a novel system called MutSensor, which allows for precise measurement of mutation rates in mammalian cells. By identifying the genes that control these mutations, the research aims to uncover fundamental mechanisms of genome stability, contributing valuable insights for public health and disease prevention.

Dr. Christine Constantinople's lab at NYU focuses on understanding how specific brain circuits, especially those involving dopamine and acetylcholine, influence learning and decision-making in changing environments. By studying rats, her research explores dynamic learning processes and how different neuromodulators can dictate whether the brain focuses on learning or movement. The lab employs advanced techniques like optogenetics and electrophysiology to manipulate and observe neural activity during learning tasks, aiming to uncover new therapeutic targets for neuropsychiatric disorders.

Dr. Brian Dynlacht's lab at NYU School of Medicine focuses on understanding how primary cilia, tiny structures on the surface of cells, are assembled and disassembled. These cilia are crucial for sensing signals from the environment and play important roles in cell growth and division. The lab studies specific proteins that help configure cilia and other cellular structures, which can have implications in developmental defects and cancer. By uncovering the connections between protein functions and cellular processes, the lab aims to advance knowledge in cell biology and potential disease mechanisms.

Dr. Stefan Feske's lab at NYU focuses on understanding how T cells and B cells regulate immune responses to infections and their roles in autoimmune diseases. The research explores the mechanisms by which ion channels affect T cell function and plasma cell differentiation, using models of inflammation and genetic screening. The ultimate goal is to identify potential drug targets that can modulate these immune responses.

Dr. Adeen Flinker's research lab focuses on understanding how our brains process speech by analyzing the way sound is integrated over time in the auditory cortex. They use advanced techniques to study patients who have had neurosurgery, allowing them to capture detailed brain activity as individuals listen to speech. The goal is to uncover how we recognize words and sentences and to develop new treatments for speech disorders.

Dr. Angela Trude's lab at New York University focuses on improving access to healthy food for low-income families, particularly through online grocery shopping. The research aims to enhance fruit, vegetable, and legume purchases among families to combat food insecurity and reduce risks related to cardiovascular diseases. The lab tests innovative strategies that involve using text messages, financial incentives, and tailored shopping lists to encourage healthier food choices while addressing barriers to online grocery shopping.

Dr. Andreas Hochwagen's lab at New York University studies how organisms safely break their DNA to create genetic diversity. They focus on understanding programmed DNA double-strand breaks and their roles in meiotic recombination and ribosomal DNA variations. By using genetics and molecular biology techniques, the lab aims to gain insights into genome stability and its implications for human diseases.

David Gresham's lab at NYU studies how cells respond to nutrient deprivation and adapt through rapid evolution. They focus on understanding cell quiescence, a state where cells remain inactive but can react to challenges, and how certain genetic changes can lead to rapid adaptations in microbes. This research has implications for improving antifungal treatments and understanding diseases influenced by genetic variation.

Dr. Andre Antonio Fenton's lab at NYU focuses on understanding how memories are formed and stored in the brain, particularly through the study of synaptic plasticity in the hippocampus. The research examines the mechanisms behind long-term memory, testing established theories on synaptic changes that occur during the learning process. By using techniques like optogenetics, the lab aims to investigate how specific neurons contribute to memory storage and what happens when these processes are disrupted.

The research lab led by James P Higham focuses on understanding how natural disasters, specifically hurricanes, influence biological aging in free-ranging rhesus macaques. By examining the effects of hurricanes on these animals, the lab aims to uncover how social support can buffer against the adverse health impacts associated with aging, particularly following such traumatic events. The findings could help inform interventions for aging populations in disaster-prone areas.

Dr. Suzanne Dikker's lab focuses on using innovative methods to study how infants develop their cognitive skills. Through remote assessments that include eye-tracking and ECG, the lab investigates how infants' attention and memory function as they grow. Their research aims to understand the relationships between caregivers and infants and how these interactions affect early development, with the goal of providing insights that could lead to better prevention and intervention strategies for developmental disorders.

Dr. Chunyuan Jin's lab focuses on understanding how formaldehyde, a chemical found in many environments, affects our DNA and contributes to cancer. The research aims to uncover how formaldehyde interacts with proteins that help package our DNA, leading to potential changes in gene expression and chromosomal stability, which might be linked to cancer development. This work could reveal new insights into how environmental toxins impact our health.

Dr. Roozbeh Kiani's lab at New York University focuses on understanding and controlling neural activity in the brain to develop new treatments for disorders like Parkinson's disease and depression. They employ advanced techniques to monitor and influence brain circuits during decision-making and movement, bridging the gap between cognitive functions and motor actions. By using data-driven methods and targeted stimulation, their research aims to advance therapies and brain-computer interface technologies, providing solutions for neurological and psychiatric conditions.

Dr. Ravinder Regatte's lab at NYU focuses on improving the diagnosis of osteoarthritis through advanced MRI techniques. By developing a method called magnetic resonance fingerprinting (MRF), the lab aims to quickly and accurately assess knee joint health without the need for contrast agents. This work not only benefits patients by providing earlier diagnosis but also aims to enhance treatment strategies for osteoarthritis.

Dr. Thorsten Kirsch’s lab focuses on understanding the biological and imaging markers related to posttraumatic osteoarthritis (PTOA) that develops after anterior cruciate ligament (ACL) injuries. The lab investigates how cellular responses and molecular changes after an injury can predict the progression of joint damage over time. By analyzing synovial fluid and utilizing advanced MRI techniques, the research aims to identify potential biomarkers for early diagnosis and treatment of PTOA.

Dr. Adolfo Cuevas's lab at NYU focuses on understanding how stress from the environment and personal relationships contributes to obesity and inflammation. The research aims to connect different types of stress to weight gain and related health issues by studying large groups of people over time. By doing this work, the lab hopes to find effective strategies to help prevent obesity and improve health, especially in older adults.

Dr. Juan Lafaille's lab at New York University focuses on understanding how specific types of immune cells, called border-associated macrophages (BAMs), maintain healthy blood vessels in the brain. This research is particularly relevant to diseases like Alzheimer's, where the buildup of amyloid proteins can disrupt vascular function. By studying unique mouse models, the lab aims to uncover the role of BAMs in preventing these complications and advancing our knowledge of brain health, aging, and neurodegenerative diseases.

Dr. Fei Li's research lab focuses on understanding the centromere, an essential chromatin domain that plays a crucial role in proper chromosome segregation during cell division. By exploring how centromeres are specified and inherited, the lab aims to uncover the molecular mechanisms behind centromere function, which is linked to various diseases, including cancer and Down syndrome. Using the fission yeast model, the lab combines different disciplines such as genetics, genomics, and structural biology to investigate the intricacies of centromere organization and regulation.

Dr. Timothee Lionnet's research lab at NYU focuses on understanding the molecular mechanisms of aging and transcription regulation. The lab uses synthetic biology and advanced imaging techniques to explore how specific proteins are involved in the aging process and how they regulate gene expression. By manipulating these proteins, the lab aims to develop innovative strategies to combat aging-related diseases and improve gene regulation technologies.