Dr. Dirk Schnappinger's lab at Weill Medical College focuses on understanding tuberculosis (TB), a major global health issue. The lab investigates the mechanisms of new antibiotics called nitroimidazoles, which are essential for treating drug-resistant TB. By studying the genetics and metabolism of the TB bacteria, the team aims to enhance treatment strategies and develop more effective drugs.

Dr. Sabine Ehrt's lab focuses on understanding the role of M. tuberculosis (Mtb) and its metabolism during infection to aid in developing new tuberculosis drugs. The research particularly examines how different environments within the human body affect Mtb's survival and growth, especially regarding its carbon source requirements. By studying drug targets in animal models that mirror human conditions, her lab aims to find innovative therapeutic approaches to combat tuberculosis, a significant global health threat.

Dr. Claire Isabelle Vanpouille-Box's lab studies glioblastoma, a challenging brain cancer, focusing on how radiation therapy affects tumor metabolism and immune responses. The lab investigates how glioblastoma cells change their metabolism to produce fatty acids and how this impacts the immune system, potentially leading to therapy resistance and tumor recurrence. By understanding these mechanisms, the research aims to find new ways to boost the immune response against these tumors after radiation treatment.

Dr. Jonathan D Victor's lab focuses on understanding how the brain processes visual information, specifically how we perceive textures and material properties. The research integrates experimental studies with computational modeling to investigate how visual data is transformed into perceptions that guide our behaviors. By developing new analytical tools and leveraging insights from psychophysics and neuroscience, this lab aims to enhance our understanding of visual perception and its implications for addressing visual processing deficits.

Dr. Yi Wang's lab focuses on developing innovative MRI techniques to improve the diagnosis and treatment of neurological conditions such as stroke and Alzheimer's disease. They use fluid mechanics principles to enhance tissue perfusion imaging and create new methods for mapping oxygen metabolism in the brain. By refining these MRI-based tools, the lab aims to provide more accurate and reliable assessments of brain health, ultimately aiding in patient management and clinical decision-making.

Dr. Zhuhao Wu's lab focuses on creating advanced resources for studying the human brain through the development of artificial intelligence-assisted recombinant antibodies. By utilizing AI algorithms, the lab aims to improve the quality and scalability of antibodies used for brain mapping, enabling detailed insights into brain structure and function. Their innovative platform will not only provide enhanced antibody tools but also create a user-friendly database for researchers worldwide.