Dr. Gabriel A. Kwong's lab at Georgia Institute of Technology focuses on innovative approaches to cancer detection and therapy using engineered T cells. The lab is developing advanced biosensing technologies that can identify dormant cancer cells, particularly in cases like estrogen receptor-positive breast cancer. By utilizing techniques such as DNA-gated sorting and T cell engineering, the lab aims to monitor the reawakening of cancer and improve therapeutic strategies for cell-based cancer treatments.

Dr. Stanislav Y. Emelianov's lab at Georgia Tech focuses on enhancing cancer therapy through innovative techniques that improve the effectiveness of CAR T cell treatment for solid tumors, such as breast cancer. By using advanced imaging methods and unique gene switches that activate CAR T cells at specific temperatures, the lab aims to deliver targeted therapy while minimizing side effects. This cutting-edge research merges engineering with cancer treatment to create safer and more effective therapeutic options for patients.

Dr. F. Levent Degertekin's lab at Georgia Tech focuses on advancing cardiac procedures through innovative catheter technology. Their latest project aims to develop a combined intravascular ultrasound (IVUS) and fractional flow reserve (FFR) microcatheter that will improve the safety and effectiveness of percutaneous coronary interventions, a common heart procedure. By integrating imaging and pressure measurement capabilities into a single device, the lab seeks to optimize patient outcomes while reducing risks and costs associated with these complex procedures.

Dr. Scott J. Hollister's lab at Georgia Tech focuses on improving medical implants and devices for various applications, including facial reconstruction and airway support in children. The research aims to understand how skin and airway tissues respond to implants and to design new, better-performing devices using advanced techniques like 3D printing and computer modeling. By studying tissue responses and complications in animal models, the lab hopes to mitigate risks associated with these devices in clinical settings.

Dr. Ravi S. Kane's lab focuses on creating innovative vaccines to tackle influenza viruses, including those responsible for historic pandemics. By engineering the protein hemagglutinin and its presentation on multivalent scaffolds, the lab aims to develop vaccines that elicit strong immune responses against the conserved parts of these viruses, which could help in managing seasonal flu and preventing future pandemics.

Dr. Susan Napier Thomas's lab focuses on developing new therapies for lymphedema, a condition that causes swelling and fibrosis due to improper lymphatic drainage, often seen in breast cancer survivors. The research involves creating innovative drug delivery systems that target lymphatic tissues to improve lymphatic function and reduce inflammation. By using pre-clinical models and advanced imaging, the lab seeks to replace outdated treatment strategies with effective drug therapies.

Dr. John Blazeck's research lab focuses on enhancing immune cell therapies to improve their effectiveness against cancer. The lab aims to manipulate the metabolism of T cells so they can better compete with tumors for nutrients and overcome the immunosuppressive environment created by cancer cells. By using the principles of synthetic biology and metabolic engineering, the lab is pioneering new ways to enhance the capabilities of T cells in fighting cancer. This work could lead to significant advancements in cancer treatments, especially for solid tumors.

Dr. Ankur Singh's lab at Georgia Tech focuses on improving our understanding of immune responses, particularly in B cells, which are crucial for fighting infections and diseases like lymphoma. They develop innovative hydrogel-based structures that mimic lymphoid tissues to study how human B cells can be activated and sustained over time. This research aims to address significant challenges in vaccine development and racial disparities in cancer outcomes.

Dr. Christopher John Rozell's lab focuses on understanding how the brain and body interact during decision-making processes that require physical effort. The lab is developing a new system to study these interactions in a naturalistic setting, especially in individuals with psychiatric disorders like depression. By measuring diverse biological signals simultaneously, the lab aims to improve our understanding of motivation and inform the development of better therapies.

Dr. Hang Lu's lab studies the aging process using the model organism C. elegans, a small worm. The lab aims to understand how behavioral changes relate to neural activity over time, especially how these dynamics affect health and longevity. Through innovative technologies and computational models, the team hopes to unveil the mechanisms behind aging, which could lead to strategies for healthier aging in various species, including humans.