Dr. Stephen David Bell's lab focuses on studying archaeal microorganisms to better understand fundamental biological processes that are also present in more complex eukaryotic cells. By investigating how archaea organize their DNA and manage gene expression, the lab aims to uncover parallels to eukaryotic systems, offering insights into evolution and essential molecular functions. Their work has significant implications for understanding the basic mechanisms of life.

Dr. Xue Han's lab at Ohio State University focuses on understanding how the immune system is regulated in lupus, an autoimmune disease. The lab is investigating a specific protein called PD-1H that plays a crucial role in controlling immune responses in tissues affected by lupus. By studying how PD-1H functions, the lab aims to develop new therapies that can better manage lupus and improve patients' health.

Jacob Yount's lab focuses on understanding how the SARS-CoV-2 virus causes severe damage to the lungs and heart, particularly in individuals with certain immune deficiencies. By studying specific immune responses and inflammatory pathways, they aim to find new ways to prevent and treat COVID-19 complications. Their research involves looking at how different proteins and immune cells contribute to disease severity, which could lead to tailored therapies for vulnerable populations.