Dr. Hyung Jin Ahn's lab focuses on understanding how vascular issues and white matter lesions contribute to motor dysfunction in Alzheimer's Disease (AD) and related disorders. They study both human brain tissues and mouse models to find out how blood vessel problems lead to damage in the brain and impair motor skills. The goal is to uncover mechanisms behind these changes and eventually develop therapies to help patients suffering from these conditions.

Dr. Steven S An's lab at Rutgers focuses on understanding asthma, specifically how inflammation affects the contraction of airway smooth muscle cells. The research aims to uncover new mechanisms that regulate airway constriction and to identify new treatments that could help patients with asthma, especially those resistant to current medications. This work is crucial for developing better therapies to manage asthma symptoms and improve patient outcomes.

Dr. Jun Wang's lab at Rutgers focuses on developing innovative antiviral therapies to combat viral infections, particularly those caused by coronaviruses like SARS-CoV-2 and non-polio enteroviruses. Their research aims to identify and optimize dual inhibitors that can target both viral and host proteins critical for viral replication, ultimately leading to effective treatments. The lab is dedicated to understanding the mechanisms of these viruses and creating therapeutic options that are urgently needed in public health.

Dr. Paula Bartlett's lab focuses on understanding how high fat diets disrupt calcium signaling in the liver, which is crucial for regulating metabolism. The research is primarily centered on non-alcoholic fatty liver disease (NAFLD) and its links to insulin resistance and type 2 diabetes. By uncovering the molecular mechanisms and the effects of diet-induced changes, the lab aims to find potential solutions for managing these common health issues.

Dr. Shuo Xiao's lab at Rutgers focuses on understanding how certain environmental chemicals and chemotherapy drugs affect female reproductive health. Their research investigates the harmful effects of per- and polyfluoroalkyl substances (PFAS), known for their persistence in the environment, on ovarian function. Additionally, they explore the mechanisms through which cancer treatments cause ovarian damage and potential strategies to protect women's fertility during cancer therapy.

Dr. Vanessa H. Routh's lab studies the effects of low blood sugar in people with diabetes, particularly how the brain senses these dangerous drops. They use innovative animal models to examine the roles of certain neurons in this process and the potential of the drug modafinil to restore awareness of hypoglycemia. This research is crucial for developing better treatments for diabetic patients who suffer from dangerous hypoglycemia without realizing it.

Dr. Tamara Minko's lab at Rutgers focuses on creating personalized medical treatments for women with ovarian cancer using advanced nanotechnology. By studying the individual genetic profiles of tumors, the lab aims to design tailored drug delivery systems that improve chemotherapy effectiveness and reduce the chances of resistance. Their work is crucial because it represents a significant advancement in treating gynecologic cancers, making therapies more personal and potentially more effective for patients.

Dr. Chintan Dave's lab focuses on understanding how multiple health conditions, known as multimorbidity, affect medication outcomes in older adults. The lab conducts research that aims to identify the best ways to prescribe medications safely and effectively, especially for elderly patients with complex health issues like chronic kidney disease. By analyzing large datasets, the lab seeks to create evidence-based guidelines that can ultimately improve treatment decisions for this vulnerable population.

Dr. Lauren M. Aleksunes' lab focuses on understanding how drugs and nutrients are transported across the placenta, which is vital for fetal development. The lab employs innovative research techniques, including computational modeling and microphysiological systems, to study transporter proteins that can affect maternal and perinatal health. By developing training opportunities for early-career scientists and clinicians, the lab aims to enhance knowledge in pharmacology, maternal-fetal medicine, and public health.

Dr. Monica J. Roth's lab focuses on understanding how retroviruses interact with host cell receptors, which is crucial for developing new antiviral drugs. By utilizing advanced computational modeling and protein structure prediction techniques, the lab aims to identify novel viral proteins and their binding partners in host cells. This research has significant implications for tackling viral diseases and cancer by exploring new strategies for drug design and therapeutic interventions.

Dr. Debra L Laskin's research lab focuses on understanding how inflammation in the lungs can lead to chronic diseases like asthma and COPD, particularly due to exposure to ozone, a common air pollutant. The lab studies macrophages, which are immune cells that can either promote inflammation or help resolve it. They are investigating ways to encourage these cells to shift from a pro-inflammatory state to a healing state, hoping to find new strategies to prevent lung injury and improve public health outcomes.