Dr. Weiqin Chen's lab focuses on understanding the role of a protein called BSCL2 in heart metabolism and function. They investigate how BSCL2 is involved in breaking down triglycerides, a type of fat, and how this process affects the health of heart cells. The ultimate goal is to uncover new insights that could lead to therapies for heart conditions caused by metabolic issues.

Dr. David L. Mattson's lab at Augusta University focuses on understanding the relationship between diet, immune response, and hypertension. The research investigates how different dietary proteins influence immune cell activity, particularly in the kidneys, and how this affects blood pressure. By using animal models, the lab aims to uncover new insights that could lead to better treatments for people suffering from hypertension, especially those who are sensitive to salt.

Dr. Justine M. Abais-Battad's lab focuses on understanding how sex differences affect hypertension, especially regarding gut health and the immune system. They conduct studies using rat models and human samples to uncover how gut bacteria and immune responses contribute to high blood pressure, particularly in females. This research aims to improve treatments for hypertension and kidney disease by identifying sex-specific mechanisms.

Dr. Riyaz Mohamed's lab at Augusta University focuses on understanding polycystic kidney disease (PKD), a genetic disorder that causes the formation of numerous cysts in the kidneys, ultimately leading to kidney failure. The lab is particularly interested in a molecule called netrin-1, which appears to play a role in promoting cyst growth. By studying how netrin-1 influences kidney cells and immune responses, the lab aims to identify new therapeutic targets to treat PKD more effectively and safely.

Dr. Jessica L. Faulkner's lab at Augusta University focuses on understanding preeclampsia, a serious pregnancy complication marked by high blood pressure. The research examines how the hormone leptin, which is found in elevated levels in preeclampsia patients, affects maternal and fetal health by causing cardiovascular issues. By using mouse models, the lab investigates the mechanisms underlying leptin's role in this condition, with the aim of developing better treatments.

Dr. Paul Michael O'Connor's lab focuses on understanding how red blood cell (RBC) trapping contributes to kidney injuries caused by ischemia. By investigating this mechanism, the lab aims to inform better treatment strategies for acute kidney injury (AKI), a life-threatening condition that often leads to chronic kidney problems. The research has the potential to change how we view and treat kidney injuries related to RBC dynamics and heme toxicity.

Dr. David Stepp's lab at Augusta University focuses on understanding how skeletal muscle health can protect against cardiovascular problems caused by obesity. The research looks at how maintaining muscle mass and performance can improve blood vessel function, potentially offering new treatment strategies for individuals with obesity who cannot exercise effectively. The lab explores the roles of specific genes and proteins in muscle and their influence on heart health.