Dr. Benhur Lee's lab is focused on researching henipaviruses and pararubulaviruses, which are serious threats to public health due to their high fatality rates and potential for causing pandemics. The lab develops antibodies that can neutralize these viruses and studies how they infect human cells. The goal is to provide effective treatments and preventive strategies against these dangerous viruses, enhancing global health security.

Dr. Jun Wang's lab at the Icahn School of Medicine is dedicated to understanding Alzheimer’s disease, especially its social behavior and neuropsychiatric symptoms. They explore how individual vulnerability to stress can affect these symptoms in mouse models, investigating ways to promote stress-resilience as a potential preventive strategy against Alzheimer's-related issues. The lab combines approaches from neuroscience to study the biological mechanisms behind stress and behavioral changes in the context of Alzheimer’s disease.

Dr. Xiang Xu's research lab focuses on understanding the neurological aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), particularly in patients who have experienced long-term effects after COVID-19, known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC). The lab utilizes advanced imaging techniques to investigate how brain metabolism and circulation differ between PASC patients and those with classic ME/CFS. This research aims to uncover potential shared mechanisms underlying these conditions, which may open up new avenues for diagnosis and treatment.

Dr. Nan Yang's research lab focuses on understanding the genetic factors that contribute to neuropsychiatric disorders such as schizophrenia and autism. By studying non-coding regions of the human genome, which are often overlooked, the lab aims to uncover how genetic variants affect neuronal function and contribute to disease risk. The goal is to develop new biological hypotheses that could lead to innovative therapeutic strategies for these complex conditions.

Dr. Tony Yuen's lab at the Icahn School of Medicine focuses on understanding how certain hormones affect brain health, particularly in relation to Alzheimer's disease in postmenopausal women. They are developing new tools to target and study the role of a hormone called follicle-stimulating hormone (FSH) in the brain, and how reducing its receptor can help alleviate memory loss and other cognitive issues associated with aging. Their research combines advanced genetic techniques and innovative viral delivery methods to explore potential treatments for these conditions.

The research lab led by Dr. Bin Zhang at the Icahn School of Medicine focuses on understanding Alzheimer's disease (AD) through the lens of cellular aging and genetic factors. By investigating the roles of senescent cells and the interaction between sex and the APOE gene, the lab aims to uncover new therapeutic targets for AD. Their innovative approaches include advanced single-cell sequencing techniques and multi-omics data analysis, enabling them to create personalized strategies for AD treatment and prevention.

Dr. Zhe Ying's lab at the Icahn School of Medicine focuses on the regeneration of salivary glands after they are damaged by radiation therapy. They are particularly interested in a gene called Smarca2, which plays a crucial role in the growth of salivary cells without promoting cancer growth. Their innovative research aims to develop techniques that can selectively enhance the recovery of salivary glands, which are vital for functions like swallowing and speaking, while minimizing the risk of cancer recurrence.

Dr. Zheng Herbert Wu's lab at the Icahn School of Medicine focuses on understanding how specific brain circuits support decision making and how the malfunctioning of these circuits can lead to psychiatric disorders like depression and addiction. By studying the premotor cortex in mice, the lab combines advanced techniques like spatial transcriptomics and in vivo imaging to identify the roles of different neuron types and their connectivity in decision-making processes. The aim is to unveil connections between genetic factors, neural behavior, and cognitive functions.

Dr. Ming-Ming Zhou's lab focuses on understanding how certain immune cells, specifically a type of T helper cell known as Th2 cells, develop and function in relation to diseases like asthma and allergies. By studying the mechanisms that control gene expression in these cells, the lab aims to uncover new targets for therapies that can better manage and potentially cure allergic diseases.