Dr. Sarah Kolibash Royse's research lab focuses on understanding the role of white matter injury in Alzheimer's disease. By investigating how this injury interacts with neurotoxic proteins and cognitive function, the lab aims to identify novel treatment targets that could improve prevention and treatment strategies for Alzheimer's. The lab utilizes advanced neuroimaging techniques and extensive patient data to explore these complex relationships.

Dr. Jonathan N Sachs' lab at the University of Minnesota focuses on innovative cell therapies to tackle neurodegenerative diseases such as Alzheimer's. By engineering macrophages from human stem cells, they aim to enhance the body’s ability to clear out damaging proteins and reduce inflammation in the brain. Their research integrates advanced genetic engineering techniques to create immune cells that can effectively target and manage Alzheimer's pathology.

Dr. Gelareh Sadigh's lab focuses on reducing financial barriers for cancer patients through innovative support programs. They aim to improve patient experiences and outcomes by enhancing communication about treatment costs and providing guidance on financial assistance. The lab's projects involve direct counseling and education to help patients navigate their healthcare costs more effectively.

Dr. Subhrajit Saha's lab at the University of Kansas Medical Center focuses on understanding how sex differences influence the body's response to radiation, particularly in the intestines. They explore ways to reduce inflammation and damage caused by radiation exposure using targeted treatments. Their research aims to identify new therapies that can be used as medical countermeasures in case of radiation accidents, helping to protect both men and women from radiation injuries.

Lonie Salkowski's lab at the University of Wisconsin-Madison focuses on improving cancer detection through enhanced training for radiology residents in screening mammography. The lab is developing a specialized simulation system to help residents practice their interpretive skills in a safe environment, aiming to reduce errors in diagnosing breast cancer. Their research combines radiology, computer science, and educational psychology to foster better outcomes for women's health.

Dr. Steven Salzberg's lab at Johns Hopkins University focuses on developing advanced computational methods to analyze and interpret genomic data. By creating new tools and databases, the lab aims to enhance our understanding of human and other genomes, improving gene discovery and genome annotation processes. This research is essential for addressing genetic diseases and expanding the knowledge of biological diversity.

Dr. Laura Santambrogio's lab focuses on understanding a newly discovered compound derived from tryptophan metabolism called 3HKA, which exhibits anti-inflammatory properties. They study how this compound interacts with immune cells, proposes its potential therapeutic applications for autoimmune diseases like psoriasis and lupus, and develop similar compounds to enhance immunomodulation. The lab integrates techniques from biochemistry and immunology to explore how metabolism influences immune system behavior.

At Dr. Dorthe Schaue's lab at UCLA, researchers focus on using a new imaging technique called autofluorescence to measure how much radiation exposure organisms have experienced. This research aims to develop a way to quickly assess radiation damage, which is crucial for making timely medical decisions during emergencies. By studying how cells respond to radiation at the molecular level, the lab hopes to create a tool that can predict acute health risks related to radiation and enhance safety protocols during radiological events.

Dr. Mark Schnitzer's lab at Stanford University focuses on understanding how different types of neurons in the brain interact and influence behavior. They have developed a groundbreaking robotic imaging system called the Octopus, which allows researchers to simultaneously observe neural activity in multiple regions of the brain. This technology aims to improve our understanding of brain function by enabling real-time imaging of genetically defined neuron types in awake animals.

Dr. Helen Schwerdt's lab focuses on understanding how dopamine plays a role in learning from rewards and punishments, which is essential for behaviors ranging from simple tasks to more complex cognitive functions. By developing advanced tools to measure dopamine levels in the brain, particularly in monkeys, the research aims to explore how different types of feedback affect learning processes. This work could have significant implications for treating Parkinson's disease and related disorders that impact these learning mechanisms.

Dr. Lonnie D. Shea's lab at the University of Michigan focuses on advanced biomedical engineering techniques to tackle major health issues like type 1 diabetes and breast cancer. The research includes developing improved pancreatic organoids and engineered scaffolds to enhance the effectiveness of cell transplants and monitor cancer progression. They aim to use innovative materials, such as nanoparticles and 3D scaffolding technologies, to improve therapeutic responses and patient outcomes.

Dr. Zhiyuan Shen's lab focuses on understanding the mechanisms by which BRCA proteins help maintain DNA integrity and influence cancer therapy. The team investigates how deficiencies in DNA repair processes contribute to cancer and how we might exploit these defects for treatment. Their research aims to improve outcomes for patients with BRCA-related cancers, such as breast cancer and medulloblastoma.

Dr. Richard E. Debski's lab focuses on understanding and improving exercise therapy for individuals with rotator cuff tears, particularly in older adults. Their research investigates how personalized exercise programs can help restore shoulder function and prevent the need for surgery, aiming to enhance patient outcomes and develop effective clinical guidelines for treatment. By analyzing biomechanical and clinical factors over time, the lab seeks to create individualized rehabilitation strategies for better long-term results.

The research lab led by Dr. Rachna Shroff at the University of Arizona focuses on enhancing cancer clinical research, especially for underrepresented populations like Hispanics and Native Americans. The lab aims to develop a comprehensive clinical trials navigation program, making cancer trials more accessible and inclusive. By expanding the reach of the Arizona Clinical Trials Network, the lab seeks to improve participation in cancer trials and advance drug development in oncology.

Dr. Nenad Bursac's lab focuses on developing advanced engineered human skeletal muscle tissues to better understand and study muscle regeneration and the role of muscle stem cells. By creating complex 3D tissue models that mimic the natural environment of muscle stem cells, the lab aims to explore how different cell types interact and how these interactions affect muscle health and recovery. This research has significant implications for treating diseases like muscular dystrophies and improving muscle repair mechanisms.

Dr. Kerwyn C. Huang's lab at Stanford University focuses on understanding the small intestinal microbiota and its implications for human health. They are developing novel techniques to collect samples from the small intestine and create a comprehensive atlas of microbes residing there. This research aims to engineer therapies that utilize these microbes to improve health outcomes, especially in conditions like Crohn's disease and bacterial overgrowth.

Dr. Marc A. Sommer's lab at Duke University focuses on improving methods to manipulate neurons in the primate brain using light-sensitive proteins called opsins. They are specifically addressing challenges in delivering these proteins effectively with viral vectors, which can face issues due to the primate immune response. Through this research, the lab aims to enhance our understanding of visual and motor systems in the brain and improve gene therapy techniques that may also translate to human applications.

Dr. Yuhua Song's lab focuses on discovering new ways to treat Alzheimer's disease by targeting a specific protein called TREM2. By using both computational and experimental approaches, the lab aims to find existing FDA-approved drugs that can enhance TREM2's function and improve immune responses affected by Alzheimer's. This research could lead to more effective drug treatments for the disease.

Dr. Pengfei Song's lab focuses on advancing ultrasound imaging technology, specifically developing a novel clip-on device that transforms standard 2D ultrasound systems into functional 3D imaging devices. This technology aims to make 3D ultrasound imaging more accessible and efficient for clinical applications, particularly in diagnosing conditions like breast cancer. The research integrates ultrasound innovation with medical device design to improve patient care.

Dr. Ismael Seanez's lab at Washington University focuses on developing non-invasive treatments for spinal cord injuries (SCI) using transcutaneous spinal cord stimulation (tSCS). The research aims to restore motor functions like walking and hand use through controlled muscle activation without invasive methods. By better understanding how different stimulation parameters affect muscle recruitment, the lab hopes to personalize rehabilitation therapies for individuals with SCI.