Dr. Gabriel A. Kwong's lab at Georgia Institute of Technology focuses on innovative approaches to cancer detection and therapy using engineered T cells. The lab is developing advanced biosensing technologies that can identify dormant cancer cells, particularly in cases like estrogen receptor-positive breast cancer. By utilizing techniques such as DNA-gated sorting and T cell engineering, the lab aims to monitor the reawakening of cancer and improve therapeutic strategies for cell-based cancer treatments.

Dr. Stanislav Y. Emelianov's lab at Georgia Tech focuses on enhancing cancer therapy through innovative techniques that improve the effectiveness of CAR T cell treatment for solid tumors, such as breast cancer. By using advanced imaging methods and unique gene switches that activate CAR T cells at specific temperatures, the lab aims to deliver targeted therapy while minimizing side effects. This cutting-edge research merges engineering with cancer treatment to create safer and more effective therapeutic options for patients.

Dr. F. Levent Degertekin's lab at Georgia Tech focuses on advancing cardiac procedures through innovative catheter technology. Their latest project aims to develop a combined intravascular ultrasound (IVUS) and fractional flow reserve (FFR) microcatheter that will improve the safety and effectiveness of percutaneous coronary interventions, a common heart procedure. By integrating imaging and pressure measurement capabilities into a single device, the lab seeks to optimize patient outcomes while reducing risks and costs associated with these complex procedures.

Dr. Scott J. Hollister's lab at Georgia Tech focuses on improving medical implants and devices for various applications, including facial reconstruction and airway support in children. The research aims to understand how skin and airway tissues respond to implants and to design new, better-performing devices using advanced techniques like 3D printing and computer modeling. By studying tissue responses and complications in animal models, the lab hopes to mitigate risks associated with these devices in clinical settings.

Dr. Ravi S. Kane's lab focuses on creating innovative vaccines to tackle influenza viruses, including those responsible for historic pandemics. By engineering the protein hemagglutinin and its presentation on multivalent scaffolds, the lab aims to develop vaccines that elicit strong immune responses against the conserved parts of these viruses, which could help in managing seasonal flu and preventing future pandemics.

Dr. Agata Rozga's lab focuses on understanding communication development in children with autism spectrum disorder (ASD), especially those who are minimally verbal. The lab employs advanced computational models to analyze early prelinguistic skills such as vocalizations, gestures, and joint attention. Their ultimate goal is to identify predictors of language outcomes to help guide interventions for children at risk of staying minimally verbal.

Dr. Susan Napier Thomas's lab focuses on developing new therapies for lymphedema, a condition that causes swelling and fibrosis due to improper lymphatic drainage, often seen in breast cancer survivors. The research involves creating innovative drug delivery systems that target lymphatic tissues to improve lymphatic function and reduce inflammation. By using pre-clinical models and advanced imaging, the lab seeks to replace outdated treatment strategies with effective drug therapies.

Dr. John Blazeck's research lab focuses on enhancing immune cell therapies to improve their effectiveness against cancer. The lab aims to manipulate the metabolism of T cells so they can better compete with tumors for nutrients and overcome the immunosuppressive environment created by cancer cells. By using the principles of synthetic biology and metabolic engineering, the lab is pioneering new ways to enhance the capabilities of T cells in fighting cancer. This work could lead to significant advancements in cancer treatments, especially for solid tumors.

Dr. Adegboyega Oyelere's lab at Georgia Tech focuses on developing new treatments for prostate cancer, particularly advanced cases known as castration-resistant prostate cancer (CRPC). The team is working on small molecules that can target the androgen receptor, which is crucial for the growth of prostate cancer cells, and the biological processes that affect how these receptors function. By creating treatment agents that can effectively inhibit cancer growth through multiple mechanisms, the lab aims to overcome current limitations of prostate cancer therapies.

Dr. Ankur Singh's lab at Georgia Tech focuses on improving our understanding of immune responses, particularly in B cells, which are crucial for fighting infections and diseases like lymphoma. They develop innovative hydrogel-based structures that mimic lymphoid tissues to study how human B cells can be activated and sustained over time. This research aims to address significant challenges in vaccine development and racial disparities in cancer outcomes.

Dr. Christopher John Rozell's lab focuses on understanding how the brain and body interact during decision-making processes that require physical effort. The lab is developing a new system to study these interactions in a naturalistic setting, especially in individuals with psychiatric disorders like depression. By measuring diverse biological signals simultaneously, the lab aims to improve our understanding of motivation and inform the development of better therapies.

Dr. M.G. Finn's research lab at the Georgia Institute of Technology focuses on developing innovative HIV vaccines that utilize controlled delivery systems to enhance immune responses. By incorporating advanced materials and strategies, such as injectable hydrogels and multivalent vaccine platforms, the lab aims to increase the longevity and efficacy of vaccine-induced immunity. Their research not only concentrates on vaccine formulation but also investigates how these vaccines work on a cellular and molecular level in various animal models.

Dr. Boris Prilutsky's lab focuses on understanding how the body controls movement, especially after spinal cord injuries (SCI). They study how spinal circuits can still help with locomotion, aiming to improve walking techniques for those affected by SCI. By examining both animal models and complex environments, the lab hopes to find new ways to enhance limb coordination and mobility for people with movement disorders.

Dr. Hang Lu's lab studies the aging process using the model organism C. elegans, a small worm. The lab aims to understand how behavioral changes relate to neural activity over time, especially how these dynamics affect health and longevity. Through innovative technologies and computational models, the team hopes to unveil the mechanisms behind aging, which could lead to strategies for healthier aging in various species, including humans.

Dr. Marvin Whiteley's lab at Georgia Tech studies the bacterium Pseudomonas aeruginosa, which causes hard-to-treat infections, especially in chronic wounds. They focus on understanding how specific small RNA molecules influence the bacteria's ability to survive and thrive in human infections. By uncovering these mechanisms, the lab aims to find better diagnostics and treatments for serious infections.

Dr. Ronghu Wu's lab at Georgia Institute of Technology focuses on understanding the roles of glycoproteins, which are proteins that have sugar molecules attached to them, in health and disease. The research is particularly relevant to conditions like cancer and infections, as these glycoproteins can serve as crucial indicators for disease diagnosis and potential drug targets. The lab develops innovative techniques to study these molecules to better understand their functions and interactions in various biological processes.