Loading university
Charles M Rice — Dr. Charles M. Rice's research lab focuses on viral infections, particularly hepatitis B and various RNA viruses, including coronaviruses. The lab seeks to understand how these viruses interact with host cells, the mechanisms by which the immune system responds to these infections, and how viral pathogenesis occurs at the cellular level. By employing advanced technologies such as RNA sequencing and single-cell analysis, the lab aims to uncover new therapeutic strategies and improve our understanding of viral diseases.
Elaine Fuchs — Dr. Elaine Fuchs' lab at Rockefeller University studies how skin stem cells contribute to tissue growth, maintenance, and healing. The research focuses on understanding how these cells communicate with their environment and respond to signals, which is crucial for maintaining healthy skin and informing regenerative medicine. By investigating the mechanisms of stem cell behavior and their role in diseases like cancer, the lab aims to develop new therapeutic strategies for skin-related disorders.
Robert G Roeder — Dr. Robert G. Roeder's lab at Rockefeller University focuses on understanding how specific proteins interact to control the formation and function of fat cells, which play a crucial role in metabolic health. The lab uses a combination of biochemical techniques and animal studies to explore how these interactions can impact conditions like obesity and diabetes. This research aims to uncover new potential treatments for metabolic disorders by examining the underlying mechanisms of fat cell behavior.
Titia De Lange — Dr. Titia De Lange's lab at Rockefeller University studies how telomeres—the protective caps at the ends of chromosomes—affect cancer and cellular aging. They investigate the mechanisms behind genome instability in tumors caused by telomere shortening, and how this can lead to issues such as replicative senescence, which limits cell proliferation. Their research aims to provide insights that could potentially inform cancer treatments and preventive strategies.
Theodora Hatziioannou — Dr. Theodora Hatziioannou's lab at Rockefeller University focuses on understanding how the body's antiviral defenses impact the ability of lentiviruses, like HIV-1, to infect hosts. By studying how specific proteins in the immune system respond to these viruses, her team aims to identify ways that lentiviruses evade detection and resistance. This research is critical for developing better strategies for preventing and treating HIV-related diseases.
Marina Caskey — Dr. Marina Caskey's lab at Rockefeller University focuses on understanding and combating viral infections, particularly HIV and hepatitis B virus (HBV). The lab conducts innovative research to investigate how HIV escapes treatments with broadly neutralizing antibodies (bNAbs) and explores new therapeutic strategies for chronic HBV infection. The goal is to improve immune responses and develop effective treatments that can lead to long-term remission of these viral infections.
Sidney Strickland — Dr. Sidney Strickland's lab at Rockefeller University focuses on understanding the mechanisms of Alzheimer's disease (AD), particularly the roles of inflammation and blood clotting. They investigate how interactions between the beta-amyloid peptide and fibrinogen contribute to cognitive decline and vascular dysfunction in AD. The lab aims to develop new therapeutic strategies by targeting these molecular interactions and understanding their impact on brain health.
Michael P Rout — Michael P Rout's lab at Rockefeller University focuses on innovative solutions to combat viral pandemics and understand important cellular structures called nuclear pore complexes. They develop advanced nanobodies from llamas to neutralize and treat infections caused by dangerous viruses like SARS-CoV-2, enhancing our preparedness for future outbreaks. Additionally, the lab investigates the structure and function of nuclear pore complexes to better understand their critical roles in gene regulation and cell function, aiming to uncover potential therapeutic targets for various diseases.
Ali H Brivanlou — Dr. Ali H. Brivanlou's lab focuses on using marmoset monkeys to study Huntington's disease, a complex neurodegenerative disorder that affects movement and cognition. The lab aims to create genetic models that mirror human conditions by employing advanced techniques like CRISPR and stem cell technologies. By understanding the molecular basis of Huntington's disease in a primate context, the research seeks to uncover new insights into its causes and how it might be treated.