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Michael Joseph Rybak — Dr. Michael Rybak's lab focuses on innovative strategies to combat difficult bacterial infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). The research emphasizes the synergy between bacteriophages and antibiotics, aiming to enhance treatment efficacy and prevent resistance. By combining these therapies, the lab seeks to improve patient outcomes and translate findings into clinical applications.
Ann G. Schwartz — Dr. Ann G. Schwartz's lab at Wayne State University focuses on understanding the genetic factors influencing cancer risk and outcomes, particularly in the African American community. The lab conducts extensive research on cancer survivors, aiming to identify genetic predispositions and barriers to genetic counseling. Their work seeks to improve cancer prevention and treatment strategies through community engagement and personalized medicine.
Zhibing Zhang — Dr. Zhibing Zhang's lab at Wayne State University focuses on understanding the development and functioning of sperm cells, with an emphasis on the mechanisms involved in spermiogenesis and fertilization. They investigate how specific proteins and complexes, like the MEIG1 complex and the IFT25/IFT27 complex, contribute to the formation of sperm flagella and the remodeling of chromatin, which is crucial for normal reproductive processes.
Antonia Abbey — Dr. Antonia Abbey's research lab studies how alcohol consumption affects behaviors and cognitive responses related to sexual aggression in social situations, particularly using virtual reality simulations. By recreating dating scenarios in a controlled environment, the lab aims to uncover the situational and cognitive factors that contribute to sexual violence, with the ultimate goal of developing effective prevention strategies.
Matthew J Allen — Dr. Matthew Allen's lab focuses on developing innovative imaging agents that can help visualize oxygen levels in the body, which is crucial for understanding diseases like cancer and kidney disorders. The lab is working on a new class of contrast agents that contain europium, a rare earth element, aiming to improve their delivery and effectiveness in medical imaging. This research has the potential to transform diagnostics and therapy for conditions associated with low oxygen levels.
James G Granneman — Dr. James G. Granneman's lab focuses on understanding how fat tissue is formed and maintained, and how it can change in response to various conditions. The research explores the interactions between different cell types in fat tissue and how these interactions can affect metabolic health. By using advanced techniques like CRISPR and spatial transcriptomics, the lab aims to shed light on how fat cells develop and function, which could lead to new treatments for obesity and diabetes.
Hyeong-Reh Choi Kim — Dr. Hyeong-Reh Choi Kim's lab focuses on developing innovative treatments for castrate-resistant prostate cancer. The research aims to create and test new therapeutic agents that target and degrade androgen receptors, helping to overcome resistance to current therapies. Using advanced animal models and molecular techniques, the lab seeks to enhance our understanding of prostate cancer progression and identify effective alternatives to existing treatments.
Pablo A. Ortiz — Dr. Pablo A. Ortiz's lab at Wayne State University focuses on understanding how proteins interact with the kidney's sodium chloride transporter, NKCC2, which plays a key role in regulating salt balance and blood pressure. Their research investigates the molecular mechanisms behind sodium reabsorption and explores the functions of proteins ALMS1 and ACTN4 in relation to hypertension and renal health. By studying these interactions, the lab aims to uncover new insights into kidney function and related diseases.
Hien M Nguyen — Dr. Hien M Nguyen's lab at Wayne State University focuses on synthesizing complex carbohydrate structures to improve medical treatments and vaccines. They are actively developing new methods for creating glycosylations, which are crucial for producing compounds that can support cancer treatments and vaccine efficiency. The lab's research aims to better understand biologically important molecules and to enhance immune responses against diseases through innovative vaccine adjuvants.