Dr. Patrick Emery's lab studies how circadian rhythms and sleep are regulated at a molecular level using fruit flies (Drosophila melanogaster). The lab focuses on understanding the genetic and cellular mechanisms that control these biological rhythms, especially how they adapt to changes in the environment. Insights from this research could have significant implications for human health, particularly regarding diseases linked to disrupted sleep patterns.

Dr. Prerana Shrestha's lab focuses on understanding how the brain forms long-term emotional memories, particularly in the context of fear and survival behaviors. The research aims to explore specific pathways in the brain that are involved in protein synthesis during memory formation and how these processes are affected in conditions like post-traumatic stress disorder (PTSD). By using mouse models and various techniques, the lab investigates the mechanisms behind memory regulation and aims to identify potential targets for therapeutic interventions.

Dr. Yun Lei's lab at Augusta University focuses on understanding how specific neurons in the brain, particularly in the entorhinal cortex, are affected by Alzheimer's disease (AD) as we age. The research investigates the role of epigenetic changes, particularly involving a protein called EZH2, in the loss of these neurons and cognitive decline associated with AD. By exploring these mechanisms, the lab aims to uncover potential therapeutic targets for preventing or mitigating AD-related neuronal damage.

Dr. Emily Johnson's research lab at Johns Hopkins University focuses on understanding late-onset epilepsy, particularly how epigenetic factors and chronic health conditions contribute to cognitive decline in older adults. The lab explores the relationship between environmental exposure, genetic markers, and cognitive performance to aid dementia prevention strategies. This work is especially relevant for the over 250,000 older adults in the U.S. suffering from this condition.

Dr. Yu Wang's lab at the University of Michigan focuses on understanding epilepsy associated with mTORopathies, particularly in how these conditions develop and progress. They use advanced techniques to explore the cellular and molecular changes in the brain that lead to epilepsy, especially in children with drug-resistant forms of the disease. The lab combines animal models with human tissue studies to investigate potential therapeutic strategies and improve seizure outcomes.

Dr. Gordon F Buchanan's lab at the University of Iowa focuses on understanding how seizures affect the brain's ability to respond to carbon dioxide, which may play a role in sudden unexpected death in epilepsy (SUDEP). By using advanced mouse models, the lab investigates the mechanisms of arousal impairment surrounding seizures and explores potential therapeutic interventions to mitigate risks associated with epilepsy.

Dr. Nuria Lacuey Lecumberri's research focuses on understanding and preventing sudden unexpected death in epilepsy (SUDEP). Her lab specifically investigates the role of forebrain networks in regulating breathing and how neuromodulation can enhance respiratory function during critical moments after seizures. By studying patients undergoing epilepsy surgery, the lab aims to develop targeted interventions that could potentially save lives.

Dr. Farrah Jasmine Mateen's lab focuses on improving access to epilepsy diagnosis in underserved populations. The team works on developing artificial intelligence tools that can help non-specialists accurately interpret EEG results, a crucial part of diagnosing epilepsy. By training AI algorithms and creating risk assessment tools, the lab aims to provide reliable diagnostic services in locations where expert care is limited, improving outcomes for many individuals affected by epilepsy.

Dr. Hannah Cranley Glass's research lab at UCSF focuses on understanding the genetic factors that influence the development of epilepsy in children who have experienced neonatal seizures. By studying a diverse cohort of children, the lab aims to identify genetic changes linked to the increased risk of epilepsy after brain injury. Their work seeks to improve prediction methods for epilepsy risk and refine treatment approaches for affected children, ultimately contributing to better health outcomes for vulnerable populations.

Dr. Esther Krook-Magnuson's lab at the University of Minnesota focuses on understanding the brain's mechanisms involved in epilepsy, particularly how the cerebellum influences seizure activity. The lab is investigating the connections between the hippocampus and the supramammillary area, aiming to reveal how these brain regions interact and affect neurological functions. Their research has the potential to lead to new treatment strategies for temporal lobe epilepsy and other neurological disorders.

Dr. Jaideep Kapur's lab at the University of Virginia focuses on understanding the brain circuits involved in a dangerous type of seizure called secondary generalized tonic-clonic seizures. The lab aims to unravel the complex pathways in the brain that contribute to these seizures, which can lead to serious health risks, including sudden death in epilepsy patients. Through a combination of imaging techniques and advanced mouse models, the team seeks to identify new therapeutic targets to improve treatment options for patients who suffer from these seizures.

Dr. Kathryn Adamiak Davis leads a research lab focused on improving treatment outcomes for patients with drug-resistant epilepsy. The lab investigates the use of biomarkers to predict how well patients will respond to a device called responsive neurostimulation (RNS) that helps control seizures. By analyzing clinical and brain activity data, the lab aims to develop a predictive signature that could guide better treatment decisions for individuals seeking relief from their seizures.

Dr. Elan D. Louis's lab focuses on exploring essential tremor (ET), a common neurological condition that affects millions of Americans. The lab is investigating the use of PET imaging to measure a potential biomarker, synaptic vesicle glycoprotein 2A (SV2A), which may help diagnose ET and track its progression, a crucial development given the lack of current biomarkers for this disease. Their research not only aims to enhance diagnostic accuracy but also aims to differentiate ET from related movement disorders.

Dr. Daniel Feldman's research lab at UC Berkeley focuses on understanding how certain brain cells, called inhibitory interneurons, regulate their activity in response to sensory experiences and learning. The lab investigates how these changes may play a role in conditions like autism, particularly looking at molecular mechanisms and plasticity in different types of interneurons. By studying how these cells can adapt in the somatosensory cortex, the research aims to uncover new therapeutic targets for improving brain function in autism and similar disorders.

Dr. Vincent P. Ferrera's research lab focuses on understanding how the brain learns and processes information, particularly in relation to working memory and inferential reasoning. The lab investigates new methods of using focused ultrasound to improve cognitive functions in models of neurological and psychiatric disorders. This research aims to pave the way for non-addictive treatments that could help those suffering from memory impairments due to conditions like Alzheimer's and schizophrenia.

Dr. Yvonne W. Wu leads research aimed at improving fetal monitoring techniques to prevent neonatal brain injuries. Her lab focuses on analyzing electronic fetal monitoring data to better predict the risk of conditions like hypoxic-ischemic encephalopathy (HIE), which can lead to serious long-term disabilities in newborns. Through advanced data analysis and machine learning methods, her research seeks to enhance clinical outcomes for infants during labor and delivery.

Dr. Angela Filous's lab at Ohio State University focuses on understanding how infections, particularly pneumonia, impact recovery after spinal cord injuries. They explore the mechanisms behind impaired recovery and aim to find ways to protect spinal cord function in patients. The lab uses various experimental models to investigate the cellular and molecular interactions involved in injury and repair processes following infection.

Dr. Andrew Findlay's lab at Washington University focuses on developing new gene therapies for muscular dystrophies, particularly a type called limb-girdle muscular dystrophy D1 (LGMDD1). Unlike other gene therapy approaches that address recessive disorders, his research targets dominantly inherited conditions where traditional methods fail. His team is pioneering a technique called allele specific knockdown (ASKD) to selectively silence harmful gene mutations while preserving normal gene function. This work is crucial for advancing the treatment landscape for similar muscular dystrophies and potentially other genetic disorders.

Dr. Karen L Fingerman's lab focuses on understanding the challenges faced by caregivers of older adults with Lewy Body Dementia (LBD). The research explores how caregivers experience stress related to caregiving tasks, the mood effects of this stress throughout the day, and the roles of personal efficacy and social support in mitigating these stresses. By studying caregivers' experiences in real-time, the lab aims to develop tailored interventions to improve their well-being.

Dr. Diasynou Fioravante's research lab at UC Davis focuses on the connections between the cerebellum and limbic system, particularly how these connections influence emotions and learned behaviors. The lab aims to understand how these brain regions interact during learning and emotional responses, which is especially important for understanding conditions like post-traumatic stress disorder. Through various experimental techniques, they investigate the underlying circuits that can improve our knowledge of psychological well-being.