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Louise D. Mccullough — Dr. Louise D. Mccullough's lab focuses on understanding how sex and age affect the body's response to neurological conditions like stroke and COVID-19. The research aims to uncover biological differences that lead to varying outcomes in men and women, especially regarding inflammation and recovery. By investigating these differences, the lab hopes to develop targeted therapies to improve treatment for all patients affected by neurological diseases.
Juneyoung Lee — Dr. Juneyoung Lee's lab at the University of Texas Health Science Center focuses on understanding the connection between the gut microbiome and brain health, particularly in disorders like Alzheimer's disease and cerebral amyloid angiopathy (CAA). The lab investigates how B cells, a type of immune cell, can influence neuroinflammation and cognitive decline as we age. Their research aims to uncover new ways to target these cells to improve outcomes for patients suffering from age-related brain diseases.
Michael C Lorenz — Dr. Michael C. Lorenz's lab at the University of Texas Health Science Center Houston focuses on understanding how a bacterial peptide can inhibit the virulence of human fungal pathogens. Their research is particularly relevant as fungal infections become increasingly resistant to existing treatments. By studying the mechanisms of this peptide, the lab aims to develop new antifungal therapies that could significantly improve health outcomes for patients with serious fungal infections.
Pramod K Dash — Dr. Pramod K Dash's research lab at the University of Texas Health Science Center focuses on understanding how inflammation affects brain injuries, particularly traumatic brain injury (TBI). The lab investigates the role of a neuropeptide called CART in controlling inflammation and its potential to enhance recovery after a TBI. By examining both central and peripheral inflammation processes, the lab aims to identify new therapeutic strategies that could improve cognitive outcomes for individuals affected by brain injuries.
John Compton Mosher — Dr. John Compton Mosher's lab focuses on developing a new digital biomarker for the early detection of Alzheimer's disease. They aim to create a noninvasive, low-cost testing method using advanced EEG technology to identify key brain signals associated with Alzheimer's. This innovative approach could revolutionize how the disease is screened, making it easier to catch in its early stages before severe symptoms appear.
Fudong Liu — Dr. Fudong Liu's lab focuses on understanding the intricate mechanisms behind stroke and neuroinflammation, particularly how gender differences and aging influence these processes. They investigate how factors like the X chromosome and hormonal changes after menopause affect stroke outcomes in women. Additionally, the lab explores the role of immune signaling pathways, specifically CD200-CD200R interactions, in modulating neuroinflammation and improving recovery from stroke.
John H Byrne — Dr. John H. Byrne's lab at the University of Texas Health Science Center focuses on understanding how different training intervals affect long-term memory and synaptic plasticity. The research seeks to uncover the biochemical mechanisms behind learning processes, specifically analyzing how various signaling molecules and transcription factors contribute to memory formation and retention. By improving these learning protocols, the lab aims to enhance methods for both animals and humans to achieve better memory outcomes.
William Margolin — Dr. William Margolin's lab at the University of Texas Health Science Center focuses on understanding how bacteria like E. coli manage to grow and divide. By studying the proteins that form their division machinery, the lab aims to uncover new insights into bacterial cell function and identify potential targets for new antibiotics. Their work combines advanced imaging techniques and molecular genetics to explore the mechanical processes in bacterial life.
Paul E Schulz — Dr. Paul E. Schulz's lab focuses on understanding how COVID-19 affects the brain, specifically investigating the long-term cognitive dysfunction that some patients experience after their recovery. They explore factors such as patient demographics and underlying inflammation that might influence cognitive decline. The lab collects data from a diverse group of individuals who were hospitalized with COVID-19, aiming to develop better treatments for those suffering from neurocognitive issues post-infection.