Dr. Adam R. Abate's lab focuses on developing innovative diagnostic technologies to improve the identification of infectious diseases and study rare cell populations involved in conditions like multiple sclerosis. The lab combines next-generation sequencing with unique methods to enhance pathogen detection and offers insights into complex cellular mechanisms by analyzing specific cell types from samples. The goal is to provide healthcare professionals with more accurate tools for diagnosing infections and understanding related diseases.

Dr. Cory Abate-Shen's research lab focuses on understanding the mechanisms of prostate cancer and bladder cancer progression. The lab employs advanced models, including genetically-engineered mice and patient-derived organoids, to investigate how specific genes and mitochondrial functions affect cancer development and metastasis. These studies aim to identify potential therapeutic targets for treatment.

Dr. Dolly Mehta's lab at the University of Illinois at Chicago focuses on understanding and treating acute lung injuries, which are often caused by infections. The research examines how certain cells in the lungs, particularly macrophages and endothelial cells, behave during inflammation and injury. By studying these cells' mechanisms, the lab aims to develop targeted therapies that protect lung function and promote healing during acute respiratory distress syndrome.

Dr. Nadav Ahituv's lab focuses on using adipose tissues (body fat) to develop innovative cancer therapies. By bioengineering fat cells to mimic brown adipose tissue, which is more effective in utilizing glucose and fat, they aim to suppress tumor growth. The lab's research is groundbreaking because it explores using engineered adipocytes (fat cells) as a form of cellular therapy to combat various types of cancer.

Dr. Hua Chen's lab focuses on understanding how selective serotonin reuptake inhibitors (SSRIs), commonly prescribed antidepressants, affect growth during puberty. By analyzing large databases of health records, the lab aims to reveal how SSRIs impact height growth in adolescents, particularly boys, and whether stopping the medication can normalize growth rates later. This research is vital for informing clinical decisions regarding the use of SSRIs in young patients.

Dr. Hyung Jin Ahn's lab focuses on understanding how vascular issues and white matter lesions contribute to motor dysfunction in Alzheimer's Disease (AD) and related disorders. They study both human brain tissues and mouse models to find out how blood vessel problems lead to damage in the brain and impair motor skills. The goal is to uncover mechanisms behind these changes and eventually develop therapies to help patients suffering from these conditions.

Dr. Kristy M. Ainslie's lab focuses on innovative therapies for challenging medical conditions such as glioblastoma and autoimmune diseases. By using biomaterials, particularly specialized biodegradable polymers, the lab aims to improve the effectiveness of immune cell therapies and develop new strategies for inducing immune tolerance. The research integrates advanced materials with cell therapy to enhance patient outcomes and advance the field of immunotherapy.

Dr. Renu Sah's lab at the University of Cincinnati focuses on understanding how airway inflammation, particularly from asthma, affects fear regulation and may contribute to conditions like PTSD. By studying mouse models, the lab investigates the immune and neural mechanisms at play, aiming to uncover potential therapeutic targets for treating fear-related disorders. Their research is particularly relevant for understanding how asthma and other pulmonary pathologies can influence mental health.

Zhi Zhong's lab at the Medical University of South Carolina focuses on understanding how alcohol affects liver function, particularly through processes involving mitochondria, the energy-producing parts of cells. They are researching how the liver responds to alcohol consumption and the resulting harm, which can lead to serious conditions like fibrosis and cirrhosis. By studying how mitochondrial health is affected by alcohol, their goal is to develop new treatments for alcohol-related liver diseases.

Dr. James Eberwine's lab at the University of Pennsylvania studies how individual brain cells respond to alcohol, especially in the context of Alcohol Use Disorder (AUD). They are using advanced techniques to look at changes in gene activity and chromatin structure in single neurons and astrocytes after alcohol exposure. The goal is to understand the underlying biology of AUD and identify potential therapeutic targets by analyzing these cellular responses in their natural brain environment.

Dr. Lingjun Li's lab focuses on advancing our understanding and diagnosis of Alzheimer's disease (AD) through innovative technologies. The research aims to discover and validate biomarkers associated with AD using advanced mass spectrometry techniques and molecular mapping strategies. By doing this, the lab hopes to shed light on the progression of AD and improve early diagnostic capabilities for this devastating disease.

Dr. Konstantin Popov's lab at the University of North Carolina Chapel Hill focuses on developing new drug discovery methods to tackle Alzheimer's disease using artificial intelligence. The lab integrates computational techniques with experimental workflows to identify and optimize small-molecule drugs that can influence key proteins involved in the disease. By combining modern technology with traditional research methods, the lab aims to create effective therapies for neurodegenerative disorders.

Dr. Kin Sing Stephen Lee's research lab focuses on developing new treatments for Alzheimer's disease, which is a growing concern as the population ages. The lab specifically aims to create inhibitors for an enzyme called soluble epoxide hydrolase (sEH), which may alleviate symptoms of the disease. Researchers will investigate how to improve the efficacy of these inhibitors to ensure they effectively reach the brain and work optimally.

Dr. Steven S An's lab at Rutgers focuses on understanding asthma, specifically how inflammation affects the contraction of airway smooth muscle cells. The research aims to uncover new mechanisms that regulate airway constriction and to identify new treatments that could help patients with asthma, especially those resistant to current medications. This work is crucial for developing better therapies to manage asthma symptoms and improve patient outcomes.

Dr. Peter L. Anderson's lab focuses on improving HIV treatment methods through the development of personalized medication dosing strategies. The research aims to validate a system that allows patients to collect their own samples and test drug levels easily at home. This work is critical for optimizing long-acting antiretroviral therapies, ensuring that each patient's treatment is tailored to their unique needs, ultimately enhancing health outcomes for individuals living with HIV.

Dr. Laura Wingler's research focuses on understanding how different drugs affect the angiotensin receptor, which plays a crucial role in regulating blood pressure. The lab investigates specific types of drug interactions with this receptor to improve treatments for cardiovascular diseases like hypertension. The ultimate goal is to design safer and more effective drugs that can target not only angiotensin receptors but also related receptors in the body.

Dr. Toni M. Antalis leads a research lab focused on understanding how blood vessels form and repair themselves, particularly in the context of cardiovascular diseases. The lab investigates the mechanisms that govern the resolution of angiogenesis, which is crucial for healing and normalizing blood flow. By studying how a specific protein called testisin affects blood vessel development, the lab aims to discover new treatments for conditions that arise from poor or excessive blood vessel formation, such as heart disease and cancer.

Dr. Paul R Carlier's lab at the University of Illinois at Chicago focuses on developing new drugs to fight malaria, a disease that affects millions worldwide. The lab is optimizing new antimalarial compounds that can target different life stages of the malaria parasite, with the goal of overcoming drug resistance. Students in the lab will learn important laboratory techniques while helping to create treatments that could save lives.

Dr. Jun Wang's lab at Rutgers focuses on developing innovative antiviral therapies to combat viral infections, particularly those caused by coronaviruses like SARS-CoV-2 and non-polio enteroviruses. Their research aims to identify and optimize dual inhibitors that can target both viral and host proteins critical for viral replication, ultimately leading to effective treatments. The lab is dedicated to understanding the mechanisms of these viruses and creating therapeutic options that are urgently needed in public health.

Dr. Christopher States' lab at the University of Louisville focuses on understanding how exposure to arsenic leads to cancer, particularly skin cancer. They investigate the role of specific microRNAs in modifying gene expression and causing chromosomal instability, which is a significant factor in tumor development. The lab develops new models to study these effects and aims to fill critical knowledge gaps in cancer etiology related to environmental exposures.